ArticleBehavioral neuroscience2020
Addiction vulnerability and the processing of significant cues: Sign-, but not goal-, tracker perceptual sensitivity relies on cue salience.
Article in Behavioral neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Sign- vs. goal-tracking is associated with greater adiposity and altered functional connectivity in response to a naturalistic food paradigm.Physiology & behavior · 2025Article
- Article
- Cortico-striatal action control inherent of opponent cognitive-motivational styles.bioRxiv : the preprint server for biology · 2024Article
- Modulation of the p75NTR during Adolescent Alcohol Exposure Prevents Cholinergic Neuronal Atrophy and Associated Acetylcholine Activity and Behavioral Dysfunction.International journal of molecular sciences · 2024Article
- Distinct cholinergic circuits underlie discrete effects of reward on attention.Frontiers in molecular neuroscience · 2024Review
- Inhibition of Dopamine Neurons Prevents Incentive Value Encoding of a Reward Cue: With Revelations from Deep Phenotyping.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Food reinforcement architecture: A framework for impulsive and compulsive overeating and food abuse.Obesity (Silver Spring, Md.) · 2023Review
- Inhibition of dopamine neurons prevents incentive value encoding of a reward cue: With revelations from deep phenotyping.bioRxiv : the preprint server for biology · 2023Article
- Article
- From skinner box to daily life: Sign-tracker phenotype co-segregates with impulsivity, compulsivity, and addiction tendencies in humans.Cognitive, affective & behavioral neuroscience · 2022Article
- Disrupted Choline Clearance and Sustained Acetylcholine ReleaseThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Comment on Pohorala et al.: Sign-tracking as a predictor of addiction vulnerability.Psychopharmacology · 2021Article
- Article
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2 authors.
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Abstract
The identification of broadly defined psychological traits that bestow vulnerability for the manifestation of addiction-like behaviors can guide the discovery of the neuronal mechanisms underlying the propensity for drug taking. Sign-tracking behavior in rats (STs) signifies the presence of a trait that predicts a relatively greater behavioral control of Pavlovian drug and reward cues than in rats that exhibit goal-tracking behavior (GTs). We previously demonstrated that relatively poor cholinergic-attentional control in STs is an essential component of the trait indexed by sign-tracking and that this trait aspect contributes to the relatively greater power of drug cues to control the behavior of STs. Here we addressed the possibility that STs and GTs employ fundamentally different psychological mechanisms for the detection of cues in attention-demanding contexts. Rats were trained to perform an operant Sustained Attention Task. As task training advanced to the stage that taxed attentional control, the relative brightness of visual target signals significantly influenced detection performance in STs but not GTs. This finding suggests that STs, but not GTs, rely on bottom-up, cue salience-driven mechanisms to detect cues. GTs may be able to resist behavioral control by Pavlovian drug cues by utilizing goal-directed decisional processes that minimize the influence of the salience of drug cues. (PsycINFO Database Record (c) 2020 APA, all rights reserved).
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