Evidence map›Paper›PMID 31916778›Full record

ArticleJournal of natural products2020

Pagoamide A, a Cyclic Depsipeptide Isolated from a Cultured Marine Chlorophyte,

Yueying Li, Hao-Bing Yu, Yi Zhang, Tiago Leao, Evgenia Glukhov, Marsha L Pierce, Chen Zhang, Hyunwoo Kim, Huanru Henry Mao, Fang Fang and 5 more

Abstract read
In one paragraph

Article in Journal of natural products, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Secondary Metabolites withMarine drugs · 2021
    Article
  7. Article
  8. Total Synthesis of Pagoamide A.Molecules (Basel, Switzerland) · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yueying LiKey Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People's Republic of China.
Hao-Bing YuCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093, United States.
Yi ZhangCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093, United States.
Tiago LeaoCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093, United States.
Evgenia GlukhovCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093, United States.
Marsha L PierceDepartment of Pharmacology, School of Medicine, Creighton University, Omaha, Nebraska 68178, United States.ORCID 0000-0002-7265-0104
Chen ZhangCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093, United States.ORCID 0000-0003-4805-0392
Hyunwoo KimCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093, United States.
Huanru Henry MaoDepartment of Computer Sciences and Engineering, University of California, San Diego, La Jolla, California 92093, United States.
Fang FangCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093, United States.
Garrison W CottrellDepartment of Computer Sciences and Engineering, University of California, San Diego, La Jolla, California 92093, United States.
Thomas F MurrayDepartment of Pharmacology, School of Medicine, Creighton University, Omaha, Nebraska 68178, United States.
Lena GerwickCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093, United States.ORCID 0000-0001-6108-9000
Huashi GuanKey Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People's Republic of China.
William H GerwickCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093, United States.ORCID 0000-0003-1403-4458

Funding

Unified Computation Tools for Natural Products ResearchR01GM107550 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI COTTRELL, GARRISON W, GERWICK, WILLIAM HENRY · 2013 to 2025
$8.2M
NIGMS NIH HHS R01 GM107550
6 · The paper itself

Abstract

A thiazole-containing cyclic depsipeptide with 11 amino acid residues, named pagoamide A (

Indexed as

American SamoaAmino AcidsAnimalsBiological ProductsChlorophytaDepsipeptidesFemaleMolecular StructureRatsTandem Mass SpectrometryAmino AcidsBiological ProductsDepsipeptides

Identifiers

PMID31916778
PMCPMC7210564

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.