Evidence map›Paper›PMID 31916765›Full record

ArticleThe journal of physical chemistry. B2020

How Do Ethanolamine Plasmalogens Contribute to Order and Structure of Neurological Membranes?

Ana West, Valeria Zoni, Walter E Teague, Alison N Leonard, Stefano Vanni, Klaus Gawrisch, Stephanie Tristram-Nagle, Jonathan N Sachs, Jeffery B Klauda

Abstract read
In one paragraph

Article in The journal of physical chemistry. B, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Special issue for Klaus Gawrisch.Biophysical journal · 2023
    Article
  8. Synthesis of ether lipids: natural compounds and analogues.Beilstein journal of organic chemistry · 2023
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ana WestDepartment of Chemistry , University of Georgia , Athens , Georgia 30602 , United States.
Valeria ZoniDepartment of Biology , University of Fribourg , 1700 Fribourg , Switzerland.
Walter E TeagueLaboratory of Membrane Biochemistry and Biophysics, National Institute on Alcohol Abuse and Alcoholism , NIH , Bethesda , Maryland 20892 , United States.
Alison N LeonardBiophysics Graduate Program , University of Maryland , College Park , Maryland 20742 , United States.
Stefano VanniDepartment of Biology , University of Fribourg , 1700 Fribourg , Switzerland.ORCID 0000-0003-2146-1140
Klaus GawrischLaboratory of Membrane Biochemistry and Biophysics, National Institute on Alcohol Abuse and Alcoholism , NIH , Bethesda , Maryland 20892 , United States.
Stephanie Tristram-NagleBiological Physics Group, Physics Department , Carnegie Mellon University , Pittsburgh , Pennsylvania 15213 , United States.ORCID 0000-0003-2271-7056
Jonathan N SachsDepartment of Biomedical Engineering , University of Minnesota , Twin Cities , Minnesota 55455 , United States.
Jeffery B KlaudaBiophysics Graduate Program , University of Maryland , College Park , Maryland 20742 , United States.ORCID 0000-0001-8725-1870

Funding

Modeling synaptic vesicles: how does alpha-Synuclein inhibit fusion?R01NS084998 · NINDS · UNIVERSITY OF MINNESOTA · PI SACHS, JONATHAN N · 2013 to 2017
$1.9M
NINDS NIH HHS R01 NS084998
6 · The paper itself

Abstract

Ethanolamine plasmalogen (EtnPLA) is a conical-shaped ether lipid and an essential component of neurological membranes. Low stability against oxidation limits its study in experiments. The concentration of EtnPLA in the bilayer varies depending on cell type and disease progression. Here we report on mixed bilayers of 1-palmitoyl-2-oleoyl-

Indexed as

Lipid BilayersMolecular Dynamics SimulationPhosphatidylcholinesPlasmalogensThermodynamics1-palmitoyl-2-oleoylphosphatidylcholineLipid Bilayersphosphatidal ethanolaminesPhosphatidylcholinesPlasmalogens

Identifiers

PMID31916765
PMCPMC8157475

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.