Evidence map›Paper›PMID 31916626›Full record

ArticleMagnetic resonance in medicine2020

JEDI: Joint Estimation Diffusion Imaging of macroscopic and microscopic tissue properties.

Lawrence R Frank, Benjamin Zahneisen, Vitaly L Galinsky

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
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  7. Active Cortex Tractography.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Lawrence R FrankCenter for Scientific Computation in Imaging, University of California at San Diego, La Jolla, CA, USA.ORCID 0000-0001-7235-587X
Benjamin ZahneisenDepartment of Radiology, Stanford University, Stanford, CA, USA.
Vitaly L GalinskyCenter for Scientific Computation in Imaging, University of California at San Diego, La Jolla, CA, USA.
University of California System · USStanford University · US

Funding

New Quantitative Neuroimaging Metrics of Structural and Functional Connectivity of the Locus Coeruleus as a Novel Biomarker of Alzheimer's Disease Pathogenesis and ProgressionR01AG054049 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BONDI, MARK W, FRANK, LAWRENCE R · 2017 to 2021
$4.1M
Diffusion Imaging in Gray MatterR01MH096100 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FRANK, LAWRENCE R · 2012 to 2016
$1.9M
NIA NIH HHS R01 AG054049NIMH NIH HHS R01 MH096100
6 · The paper itself

Abstract

purposeA new method for enhancing the sensitivity of diffusion MRI (dMRI) by combining the data from single (sPFG) and double (dPFG) pulsed field gradient experiments is presented.

methodsThis method uses our JESTER framework to combine microscopic anisotropy information from dFPG experiments using a new method called diffusion tensor subspace imaging (DiTSI) to augment the macroscopic anisotropy information from sPFG data analyzed using our guided by entropy spectrum pathways method. This new method, called joint estimation diffusion imaging (JEDI), combines the sensitivity to macroscopic diffusion anisotropy of sPFG with the sensitivity to microscopic diffusion anisotropy of dPFG methods.

resultsIts ability to produce significantly more detailed anisotropy maps and more complete fiber tracts than existing methods within both brain white matter (WM) and gray matter (GM) is demonstrated on normal human subjects on data collected using a novel fast, robust, and clinically feasible sPFG/dPFG acquisition.

conclusionsThe potential utility of this method is suggested by an initial demonstration of its ability to mitigate the problem of gyral bias. The capability of more completely characterizing the tissue structure and connectivity throughout the entire brain has broad implications for the utility and scope of dMRI in a wide range of research and clinical applications.

Indexed as

Diffusion Tensor ImagingWhite MatterAnisotropyBrainDiffusion Magnetic Resonance ImagingHumansdiffusion anisotropydiffusion tensor imaging (DTI)diffusion tensor subspace imaging (DiTSI)diffusion weighted imaging (DWI)fiber tractographygray matterjoint estimation diffusion imaging (JEDI)white matter

Identifiers

PMID31916626
PMCPMC7180135
OpenAlexW2998923455

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.