Evidence map›Paper›PMID 31916625›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2020

S100A6 is a positive regulator of PPP5C-FKBP51-dependent regulation of endothelial calcium signaling.

Barnita Haldar, Caleb L Hamilton, Viktoriya Solodushko, Kevin A Abney, Mikhail Alexeyev, Richard E Honkanen, Jonathan G Scammell, Donna L Cioffi

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Depletion ofFrontiers in molecular biosciences · 2022
    Article
  6. Article
  7. S100A6 and Its Brain Ligands in Neurodegenerative Disorders.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Barnita HaldarDepartments of Biochemistry and Molecular Biology, University of South Alabama, Mobile, AL, USA.
Caleb L HamiltonDepartment of Anatomy and Molecular Medicine, Alabama College of Osteopathic Medicine, Dothan, AL, USA.
Viktoriya SolodushkoDepartments of Biochemistry and Molecular Biology, University of South Alabama, Mobile, AL, USA.
Kevin A AbneyDepartments of Biochemistry and Molecular Biology, University of South Alabama, Mobile, AL, USA.
Mikhail AlexeyevCenter for Lung Biology, University of South Alabama, Mobile, AL, USA.
Richard E HonkanenDepartments of Biochemistry and Molecular Biology, University of South Alabama, Mobile, AL, USA.
Jonathan G ScammellComparative Medicine, University of South Alabama, Mobile, AL, USA.
Donna L CioffiDepartments of Biochemistry and Molecular Biology, University of South Alabama, Mobile, AL, USA.
University of South Alabama · USAlabama College of Osteopathic Medicine · US

Funding

T-type Calcium Channels and von Willebrand Factor ReleaseP01HL066299 · NHLBI · UNIVERSITY OF SOUTH ALABAMA · PI ALVAREZ, DIEGO F. · 2001 to 2022
$34.6M
Immunophilins regulate SOC entry channels in pulmonary endothelial cellsR01HL107778 · NHLBI · UNIVERSITY OF SOUTH ALABAMA · PI CIOFFI, DONNA L · 2013 to 2016
$1.5M
Immunophilins regulate SOC entry channels in pulmonary endothelial cellsR56HL107778 · NHLBI · UNIVERSITY OF SOUTH ALABAMA · PI CIOFFI, DONNA L · 2018 to 2018
$385k
NHLBI NIH HHS P01 HL066299NHLBI NIH HHS R01 HL107778NHLBI NIH HHS R56 HL107778NIH HHS 000927
6 · The paper itself

Abstract

I

Indexed as

Calcium SignalingAnimalsCell Cycle ProteinsCells, CulturedEndothelial CellsEndothelium, VascularLungNuclear ProteinsPhosphoprotein PhosphatasesProtein BindingProtein TransportRatsS100 Calcium Binding Protein A6Tacrolimus Binding Protein 5Tacrolimus Binding ProteinsTRPC Cation ChannelsCell Cycle ProteinsNuclear ProteinsPhosphoprotein Phosphatasesprotein phosphatase 5S100a6 protein, ratS100 Calcium Binding Protein A6Tacrolimus Binding Protein 5Tacrolimus Binding ProteinsTRPC4 ion channelTRPC Cation Channelscalcium entryendothelial barrierendothelial ISOC

Identifiers

PMID31916625
PMCPMC7401177
OpenAlexW2999933654

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.