ArticleActa psychiatrica Scandinavica2020
Actigraphic patterns, impulsivity and mood instability in bipolar disorder, borderline personality disorder and healthy controls.
Article in Acta psychiatrica Scandinavica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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17 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Toward a Digital Future in Bipolar Disorder Assessment: A Systematic Review of Disruptions in the Rest-Activity Cycle as Measured by Actigraphy.Frontiers in psychiatry · 2022Pooled it
- Validation of the English version of the Mood Rhythm Instrument.BMC psychology · 2020Trial
- Digital tools for assessing bipolar disorder: A scoping review of the current landscape.Neuroscience applied · 2026Article
- Sleep disturbance and maladaptive sleep-related cognitions in borderline personality disorder in the longitudinal McLean Study of Adult Development.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
- Tracing the hidden links between sadness, aggression, and peer victimization in adolescents.World journal of psychiatry · 2025Article
- The implementation of digital biomarkers in the diagnosis, treatment and monitoring of mood disorders: a narrative review.Frontiers in digital health · 2025Review
- Associations between Aircraft Noise, Sleep, and Sleep-Wake Cycle: Actimetric Data from the UK Biobank Cohort near Four Major Airports.Environmental health perspectives · 2024Article
- The influence of childhood trauma and chronotype on suicide attempts in Chinese emerging adults with severe depressive symptoms.BMC psychology · 2024Article
- Emotions as computations.Neuroscience and biobehavioral reviews · 2023Review
- Circadian Rhythm Alterations May be Related to Impaired Resilience, Emotional Dysregulation and to the Severity of Mood Features in Bipolar I and II Disorders.Clinical neuropsychiatry · 2022Article
- A service evaluation of short-term mentalisation based treatment for personality disorder.BJPsych open · 2021Article
- The Emerging Circadian Phenotype of Borderline Personality Disorder: Mechanisms, Opportunities and Future Directions.Current psychiatry reports · 2021Review
- Blood pressure in bipolar disorder: evidence of elevated pulse pressure and associations between mean pressure and mood instability.International journal of bipolar disorders · 2021Article
- Disturbances of Continuous Sleep and Circadian Rhythms Account for Behavioral Difficulties in Children with Autism Spectrum Disorder.Journal of clinical medicine · 2020Article
- Using Chronobiological Phenotypes to Address Heterogeneity in Bipolar Disorder.Molecular neuropsychiatry · 2020Review
- Actigraphic patterns, impulsivity and mood instability in bipolar disorder, borderline personality disorder and healthy controls.Acta psychiatrica Scandinavica · 2020Article
- Unremitting Suicidality in Borderline Personality Disorder: A Single Case Study and Discussion of Technology in Clinical Care.Harvard review of psychiatryArticle
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4 authors at 3 institutions in 1 country.
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Abstract
objectivesTo differentiate the relation between the structure and timing of rest-activity patterns and symptoms of impulsivity and mood instability in bipolar disorder (BD), borderline personality disorder (BPD) and healthy controls (HC).
methodsEighty-seven participants (31 BD, 21 BPD and 35 HC) underwent actigraph monitoring for 28 days as part of the Automated Monitoring of Symptom Severity (AMoSS) study. Impulsivity was assessed at study entry using the BIS-11. Mood instability was subsequently longitudinally monitored using the digital Mood Zoom questionnaire.
resultsBPD participants show several robust and significant correlations between non-parametric circadian rest-activity variables and worsened symptoms. Impulsivity was associated with low interdaily stability (r = -0.663) and weak amplitude (r = -0.616). Mood instability was associated with low interdaily stability (r = -0.773), greater rhythm fragmentation (r = 0.662), weak amplitude (r = -0.694) and later onset of daily activity (r = 0.553). These associations were not present for BD or HCs. Classification analysis using actigraphic measures determined that later L5 onset reliably distinguished BPD from BD and HC but did not sufficiently discriminate between BD and HC.
conclusionsRest-activity pattern disturbance indicative of perturbed sleep and circadian function is an important predictor of symptom severity in BPD. This appears to validate the greater subjective complaints of BPD individuals that are sometimes regarded as exaggerated by clinicians. We suggest that treatment strategies directed towards improving sleep and circadian entrainment may in the future be investigated in BPD.
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