Evidence map›Paper›PMID 31916152›Full record

ArticleEnvironmental science and pollution research international2020

Development, larvicide activity, and toxicity in nontarget species of the Croton linearis Jacq essential oil nanoemulsion.

Jesus Rafael Rodriguez Amado, Ariadna Lafourcade Prada, Jesus Garcia Diaz, Raimundo Nonato Picanço Souto, Júlio Cesar Escalona Arranz, Tatiane Pereira de Souza

Abstract read
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In one paragraph

Article in Environmental science and pollution research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  4. Targeting the vector of arbovirusesBeilstein journal of nanotechnology · 2025
    Review
  5. Beilstein journal of nanotechnology · 2025
    Article
  6. Chemistry and Bioactivity ofMolecules (Basel, Switzerland) · 2023
    Article
  7. Larvicidal Potential of Caribbean Plants.BioMed research international · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Molecules (Basel, Switzerland) · 2020
    Article
  14. Botanical insecticide-based nanosystems for the control of Aedes (Stegomyia) aegypti larvae.Environmental science and pollution research international · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jesus Rafael Rodriguez AmadoDepartment of Pharmacy, Faculty of Natural Sciences, Universidad de Oriente, Patricio Lumumba S/N, CP 90500, Santiago de Cuba, Cuba. jiribilla2009@gmail.com.ORCID http://orcid.org/0000-0001-7574-6219
Ariadna Lafourcade PradaDepartment of Pharmacy, Faculty of Natural Sciences, Universidad de Oriente, Patricio Lumumba S/N, CP 90500, Santiago de Cuba, Cuba.
Jesus Garcia DiazDepartment of Pharmacy, Faculty of Natural Sciences, Universidad de Oriente, Patricio Lumumba S/N, CP 90500, Santiago de Cuba, Cuba.
Raimundo Nonato Picanço SoutoBiological Sciences Department, Federal University of Amapá, Rod. Juscelino Kubitschek, KM 02, S/N - Jardim Marco Zero, Macapá, AP, 68903-419, Brazil.
Júlio Cesar Escalona ArranzDepartment of Pharmacy, Faculty of Natural Sciences, Universidad de Oriente, Patricio Lumumba S/N, CP 90500, Santiago de Cuba, Cuba.
Tatiane Pereira de SouzaLaboratory of Innovation and Development in Pharmaceutical Technology, University of Amazonas, Ave. Rodrigo Otavio, Japiim, Ramos 6200, Coroado,, Manaus, AM, CEP69077-000, Brazil.

Funding

Fundação de Amparo à Pesquisa do Estado do Amazonas 23038.000516/2013-01
6 · The paper itself

Abstract

In this study, the essential oil (EO) from leaves of Croton linearis Jacq was extracted and characterized by GC/MS. The EO hydrophilic-lipophilic balance required (rHLB) for nanoemulsion (NE) development was determined by the Griffin' method. For evaluating the larvicidal effect against Aedes aegypti, the preparation process of NE was optimized, using a central composite design. It was also evaluated the possible toxic effect of NE in nontarget species. The leaves of C. linearis contain 1.50% of EO, enclosing 61 volatile compounds, mainly eucalyptol (26.66%). The best surfactant, oil:water ratio (4.5-5.0-91.5; % w:w:w), allows to achieve the optimal NE, using a stirring speed of 800 rpm, the addition rate of 0.5 ml/min, and a stirring time of 30 min. NE (with particle size = 163 nm) showed a larvicide effect (LC

Indexed as

AedesCrotonInsecticidesOils, VolatileAnimalsLarvaMosquito VectorsPlant LeavesInsecticidesOils, VolatileCytotoxicityLarvicideNanomaterialNanosystemsOral acute toxicity

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.