Evidence map›Paper›PMID 31916007›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2020

Age and gender differences in financial distress among hematopoietic cell transplant survivors.

Salene M W Jones, Jean C Yi, Heather S L Jim, Alison W Loren, Navneet S Majhail, Joseph Uberti, Victoria Whalen, Wendy M Leisenring, Mary E D Flowers, Stephanie J Lee and 1 more

Registry-linked trialAbstract read
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06922188 (Development of Measures to Screen for Financial Hardship in Alzheimer's Disease and Dementia), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06922188 recruitingnot on this mapstarted 2025, after this paper: background citation

Development of Measures to Screen for Financial Hardship in Alzheimer's Disease and Dementia

TypeobservationalSponsorFred Hutchinson Cancer CenterRan2025 to 2029Enrolled2,460ConditionsFinancial Hardship, Alzheimer&#39, s Disease (AD), Alzheimer&#39
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Sociodemographic disparities and reasons for delayed healthcare among U.S. cancer survivors: an All of Us study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  11. Review
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  14. Pre-Surgery Inflammatory and Angiogenesis Biomarkers as Predictors of 12-Month Cancer-Related Distress: Results from the ColoCare Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Financial hardship among cancer survivors in Southern New Jersey.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
  19. Patient-reported financial toxicity, quality of life, and health behaviors in insured US cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
  20. Driving Distance and Patient-Reported Outcomes in Hematopoietic Cell Transplantation Survivors.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Salene M W JonesFred Hutchinson Cancer Research Center, Seattle, WA, USA.ORCID http://orcid.org/0000-0003-2140-5798
Jean C YiFred Hutchinson Cancer Research Center, Seattle, WA, USA.
Heather S L JimMoffitt Cancer Center, Tampa, FL, USA.
Alison W LorenUniversity of Pennsylvania, Philadelphia, PA, USA.
Navneet S MajhailCleveland Clinic, Cleveland, OH, USA.
Joseph UbertiBarbara Ann Karmanos Cancer Institute, Detroit, MI, USA.
Victoria WhalenUniversity of Nebraska, Omaha, NB, USA.
Wendy M LeisenringFred Hutchinson Cancer Research Center, Seattle, WA, USA.
Mary E D FlowersFred Hutchinson Cancer Research Center, Seattle, WA, USA.
Stephanie J LeeFred Hutchinson Cancer Research Center, Seattle, WA, USA.
Karen L SyrjalaFred Hutchinson Cancer Research Center, Seattle, WA, USA. ksyrjala@fredhutch.org.

Funding

Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Eric Collisson · 1985 to 2026
$296.4M
VIRUS-MEDIATED MYELOSUPPRESSIONP01CA018029 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI STEPHANIE J LEE · 1985 to 2026
$128.4M
Integrating health informatics in a scalable stepped care self-management program for survivors after hematopoietic cell transplantationR01CA215134 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BAKER, KEVIN S, MAJHAIL, NAVNEET S. · 2017 to 2022
$3.6M
Improving Survivorship Care for Adolescents and Young Adults: a Mixed Methods Study of Alignment with the National Standards for Survivorship CareU01CA246659 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BAKER, KEVIN S · 2020 to 2025
$3.6M
Internet Studies to Enhance Long Term Survivorship after Hematologic MalignancyR01CA160684 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI SYRJALA, KAREN LESLIE · 2011 to 2015
$3.4M
Interdisciplinary Studies to Enhance Long Term SurvivalR01CA112631 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI SYRJALA, KAREN LESLIE · 2005 to 2010
$2.8M
NCI NIH HHS P01 CA018029NCI NIH HHS P30 CA015704NCI NIH HHS R01 CA112631NCI NIH HHS R01 CA160684NCI NIH HHS R01 CA215134NCI NIH HHS U01 CA246659
6 · The paper itself

Abstract

purposeCancer has long-term financial consequences. Adolescent and young adult (AYA) and middle-aged cancer survivors may experience more financial toxicity than older adults. This study examined age differences in financial distress in hematopoietic cell transplant survivors and whether these differences result from measurement bias, more financial barriers to care, or an overall higher level of distress.

methodsHematologic malignancy survivors (n = 1135, 2-10 years post-transplant) completed the Cancer and Treatment Distress Scale (CTXD) and demographics as part of the baseline assessment for a randomized clinical trial. The CTXD has seven subscales, but for this study, we examined the financial distress subscale and the overall score. Item response theory analyses tested for bias by age and gender. Multivariate linear regression tested the association of age and gender with the CTXD scores while controlling for financial barriers to care.

resultsNo bias was found on the CTXD. AYA (p < 0.01) and middle-aged adults (p < 0.001) reported more financial and overall distress than older (age 65+) adults. The same association of age and financial distress was observed in women (p < 0.01). However, only middle-aged men (p < 0.01) reported more financial and overall distress than older men; AYA men did not (p > 0.18). Financial barriers to care were not associated with financial or overall distress.

conclusionsPart of the increase in financial distress with younger age may be due to a higher risk of general distress. Policy initiatives to control cancer costs should consider life stage and the unique financial challenges at different ages for men and women.

Indexed as

AdolescentAdultAge FactorsCancer SurvivorsFemaleGender IdentityHematopoietic Stem Cell TransplantationHumansMaleQuality of LifeTransplantation ConditioningYoung AdultEconomic problemsEconomic well-beingFinancial burdenFinancial healthFinancial toxicity

Identifiers

PMID31916007
PMCPMC7340568

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.