ArticleWorld journal of surgery2020
The Association Between Chronic Lymphocytic Thyroiditis and the Progress of Papillary Thyroid Cancer.
Article in World journal of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 4 of them syntheses that pooled it.
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Who cites it
39 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- The dual oncogenic and protective roles of hashimoto's thyroiditis in papillary thyroid carcinoma: a cohort-based meta-analysis.World journal of surgical oncology · 2026Pooled it
- Hashimoto's thyroiditis reduces central lymph node metastasis risk in papillary thyroid microcarcinoma: an integrated meta-analysis.Frontiers in endocrinology · 2025Pooled it
- Association between Hashimoto thyroiditis and clinical outcomes of papillary thyroid carcinoma: A meta-analysis.PloS one · 2022Pooled it
- Hashimoto's Thyroiditis: A "Double-Edged Sword" in Thyroid Carcinoma.Frontiers in endocrinology · 2022Pooled it
- Development and validation of an ultrasound-based deep learning radiomics nomogram for risk assessment of lymph node metastasis in papillary thyroid microcarcinoma.Quantitative imaging in medicine and surgery · 2026Article
- Association between autoimmune thyroiditis and clinicopathological features of papillary thyroid carcinoma: a prospective study.Archives of endocrinology and metabolism · 2026Article
- The role of age and antibodies in central regional lymph node metastases of papillary thyroid carcinoma combined with hashimoto's thyroiditis.BMC cancer · 2026Article
- Hashimoto Thyroiditis and Progression of Papillary Thyroid Cancer: 10-Year Retrospective Cohort Study.JMIR cancer · 2026Article
- Dual Role of AITD in TgAb-Positive PTC: Delayed Antibody Clearance with Enhanced RAIT Response.Cancer management and research · 2026Article
- Hashimoto's Thyroiditis Shows Sex- and Age-Dependent Inverse Associations with Papillary Thyroid Carcinoma Progression: A Propensity Score-Matched Analysis of 6963 Surgical Cases.Annals of surgical oncology · 2025Article
- Risk factors for postoperative recurrence of differentiated thyroid cancer: a retrospective study.Scientific reports · 2025Article
- Chronic Lymphocytic Thyroiditis Does Not Worsen Early Surgical Outcomes in Papillary Thyroid Cancer.World journal of surgery · 2025Article
- The effect of glycolytic enzyme expression and thyroiditis on the aggressiveness of papillary thyroid carcinoma: a retrospective cohort study.Annals of surgical treatment and research · 2025Article
- Clinicopathological features of follicular thyroid carcinoma coexisting with papillary thyroid carcinoma.Endocrine journal · 2025Article
- Article
- Multifocal cancer is associated with better survival than solitary cancer in non-Hispanic White patients with thyroid carcinoma.Gland surgery · 2025Article
- Prevalence of Hashimoto's thyroiditis in papillary thyroid cancer and its association with aggressive characteristics.Gland surgery · 2025Article
- Research Progress on the Immunological Correlation Between Papillary Thyroid Carcinoma and Hashimoto's Thyroiditis.Journal of immunology research · 2025Review
- Germline polymorphisms of the NOD2 pathway may predict the effectiveness of radioiodine in differentiated thyroid cancer treatment.Journal of endocrinological investigation · 2024Article
- Multi-UniFocality (MUF), in contrast to multifocality, in thyroid lesions: Relation to lymphocytic thyroiditis.Pathology international · 2024Article
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Authors and funding
4 authors.
Funding
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Abstract
backgroundWhether chronic lymphocytic thyroiditis (CLT) influences the risk of development and the progression of papillary thyroid cancer (PTC) remains uncertain. We investigated the effects of CLT on the clinicopathologic features and prognosis of PTC.
methodsTwo thousand nine hundred twenty-eight consecutive patients with PTC treated between 2009 and 2017 were divided into two groups: one with chronic lymphocytic thyroiditis and one without; 1174 (40%) of the patients had coincident CLT.
resultsIn univariate analysis, CLT correlated positively with small tumor size, frequent extrathyroidal extension, multifocal diseases, and p53 but negatively with central lymph node (LN) metastasis and BRAF mutation. In multivariate analysis, CLT was associated with extrathyroidal extension and multifocal disease; however, it was not a prognostic factor for recurrence even though it was associated with two aggressive factors. Compared with patients with PTC alone, there were more retrieved central LNs in the PTC + CLT group, and these patients also underwent more invasive diagnostic tests such as fine needle aspiration cytology and frozen biopsy of LN.
conclusionsThe CLT patients with PTC had better behavior features and prognoses than did those with PTC alone despite frequent multifocality and extrathyroidal extension. However, precaution may be necessary to avoid performing invasive diagnostic procedures for lateral LN metastasis and to manage the patients appropriately.
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