Evidence map›Paper›PMID 31915927›Full record

ArticleActa diabetologica2020

Estimating the risk of gestational diabetes mellitus based on the 2013 WHO criteria: a prediction model based on clinical and biochemical variables in early pregnancy.

Katrien Benhalima, Paul Van Crombrugge, Carolien Moyson, Johan Verhaeghe, Sofie Vandeginste, Hilde Verlaenen, Chris Vercammen, Toon Maes, Els Dufraimont, Christophe De Block and 9 more

Open access · greenAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Acta diabetologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 1 country.

Katrien BenhalimaDepartment of Endocrinology, University Hospital Gasthuisberg, KU Leuven, Herestraat 49, 3000, Louvain, Belgium. katrien.benhalima@uzleuven.be.ORCID http://orcid.org/0000-0002-3325-0263
Paul Van CrombruggeDepartment of Endocrinology, OLV ziekenhuis Aalst-Asse-Ninove, Moorselbaan 164, 9300, Aalst, Belgium.
Carolien MoysonDepartment of Endocrinology, University Hospital Gasthuisberg, KU Leuven, Herestraat 49, 3000, Louvain, Belgium.
Johan VerhaegheDepartment of Obstetrics and Gynecology, University Hospital Gasthuisberg, KU Leuven, Herestraat 49, 3000, Louvain, Belgium.
Sofie VandeginsteDepartment of Obstetrics and Gynecology, OLV ziekenhuis Aalst-Asse-Ninove, Moorselbaan 164, 9300, Aalst, Belgium.
Hilde VerlaenenDepartment of Obstetrics and Gynecology, OLV ziekenhuis Aalst-Asse-Ninove, Moorselbaan 164, 9300, Aalst, Belgium.
Chris VercammenDepartment of Endocrinology, Imelda ziekenhuis, Imeldalaan 9, 2820, Bonheiden, Belgium.
Toon MaesDepartment of Endocrinology, Imelda ziekenhuis, Imeldalaan 9, 2820, Bonheiden, Belgium.
Els DufraimontDepartment of Obstetrics and Gynecology, Imelda ziekenhuis, Imeldalaan 9, 2820, Bonheiden, Belgium.
Christophe De BlockDepartment of Endocrinology-Diabetology-Metabolism, Antwerp University Hospital, Wilrijkstraat 10, 2560, Edegem, Belgium.
Yves JacquemynDepartment of Obstetrics and Gynecology, Antwerp University Hospital, Wilrijkstraat 10, 2560, Edegem, Belgium.
Farah MekahliDepartment of Endocrinology, Kliniek St-Jan Brussel, Kruidtuinlaan 32, 1000, Brussels, Belgium.
Katrien De ClippelDepartment of Obstetrics and Gynecology, Kliniek St-Jan Brussel, Kruidtuinlaan 32, 1000, Brussels, Belgium.
Annick Van Den BruelDepartment of Endocrinology, AZ St Jan Brugge, Ruddershove 10, 8000, Brugge, Belgium.
Anne LoccufierDepartment of Obstetrics and Gynecology, AZ St Jan Brugge, Ruddershove 10, 8000, Brugge, Belgium.
Annouschka LaenenCenter of Biostatics and Statistical Bioinformatics, KU Leuven, Kapucijnenvoer 35 bloc d - box 7001, 3000, Louvain, Belgium.
Caro MinschartDepartment of Endocrinology, University Hospital Gasthuisberg, KU Leuven, Herestraat 49, 3000, Louvain, Belgium.
Roland DevliegerDepartment of Obstetrics and Gynecology, University Hospital Gasthuisberg, KU Leuven, Herestraat 49, 3000, Louvain, Belgium.
Chantal MathieuDepartment of Endocrinology, University Hospital Gasthuisberg, KU Leuven, Herestraat 49, 3000, Louvain, Belgium.
KU Leuven · BEImelda Hospital · BEOnze Lieve Vrouwziekenhuis Hospital · BEAZ Sint-Jan · BEAntwerp University Hospital · BEStatistics Belgium · BEUniversity of Antwerp · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsWe aimed to develop a prediction model based on clinical and biochemical variables for gestational diabetes mellitus (GDM) based on the 2013 World Health Organization (WHO) criteria.

methodsA total of 1843 women from a Belgian multi-centric prospective cohort study underwent universal screening for GDM. Using multivariable logistic regression analysis, a model to predict GDM was developed based on variables from early pregnancy. The performance of the model was assessed by receiver-operating characteristic (AUC) analysis. To account for over-optimism, an eightfold cross-validation was performed. The accuracy was compared with two validated models (van Leeuwen and Teede).

resultsA history with a first degree relative with diabetes, a history of smoking before pregnancy, a history of GDM, Asian origin, age, height and BMI were independent predictors for GDM with an AUC of 0.72 [95% confidence interval (CI) 0.69-0.76)]; after cross-validation, the AUC was 0.68 (95% CI 0.64-0.72). Adding biochemical variables, a history of a first degree relative with diabetes, a history of GDM, non-Caucasian origin, age, height, weight, fasting plasma glucose, triglycerides and HbA

conclusionsA model based on easy to use variables in early pregnancy has a moderate accuracy to predict GDM based on the 2013 WHO criteria.

Indexed as

Models, StatisticalAdultBelgiumBiomarkersBlood GlucoseBody Mass IndexCohort StudiesDiabetes, GestationalFemaleGestational AgeGlucose Tolerance TestGlycated HemoglobinHumansPregnancyPregnancy Trimester, FirstPrenatal DiagnosisBiomarkersBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanTriglycerides2013 WHO criteriaGestational diabetes mellitusPredictionRisk factors

Identifiers

PMID31915927
OpenAlexW2999968498

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.