Evidence map›Paper›PMID 31915245›Full record

ArticleThe Journal of biological chemistry2020

The motif E

Loreleï Durand, Stéphanie Duval, Alexandra Evagelidis, Johann Guillemot, Vahid Dianati, Emilia Sikorska, Peter Schu, Robert Day, Nabil G Seidah

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

Loreleï DurandLaboratory of Biochemical Neuroendocrinology, Clinical Research of Montreal, affiliated with Université de Montréal, Montreal, Quebec H2W 1R7, Canada.
Stéphanie DuvalLaboratory of Biochemical Neuroendocrinology, Clinical Research of Montreal, affiliated with Université de Montréal, Montreal, Quebec H2W 1R7, Canada.
Alexandra EvagelidisLaboratory of Biochemical Neuroendocrinology, Clinical Research of Montreal, affiliated with Université de Montréal, Montreal, Quebec H2W 1R7, Canada.
Johann GuillemotCIRI, Centre International de Recherche en Infectiologie, Team Pathogenesis of Legionella, INSERM U1111, Université Claude Bernard Lyon 1, CNRS UMR5308, École Normale Supérieure de Lyon, Université Lyon, Villeurbanne, 69100 France.
Vahid DianatiInstitut de Pharmacologie de Sherbrooke, Department of Surgery/Urology Division, and Faculté de Médecine et des Sciences de la Santé, Sherbrooke, Quebec J 1H 5N4, Canada.
Emilia SikorskaFaculty of Chemistry, University of Gdańsk, Gdańsk, 80-233 Poland.
Peter SchuDepartment of Cellular Biochemistry, University Medical Center, Göttingen, Humboldtallee 23, 37073 Goettingen, Germany.
Robert DayInstitut de Pharmacologie de Sherbrooke, Department of Surgery/Urology Division, and Faculté de Médecine et des Sciences de la Santé, Sherbrooke, Quebec J 1H 5N4, Canada.
Nabil G SeidahLaboratory of Biochemical Neuroendocrinology, Clinical Research of Montreal, affiliated with Université de Montréal, Montreal, Quebec H2W 1R7, Canada. Electronic address: seidahn@ircm.qc.ca.
Montreal Clinical Research Institute · CAUniversité de Sherbrooke · CAUniversitätsmedizin Göttingen · DEUniversité Claude Bernard Lyon 1 · FRUniversity of Gdańsk · PL

Funding

CIHR 148363
6 · The paper itself

Abstract

Many secretory proteins are activated by cleavage at specific sites. The proprotein convertases (PCs) form a family of nine secretory subtilisin-like serine proteases, seven of which cleave at specific basic residues within the

Indexed as

Amino Acid MotifsAmino Acid SequenceAntigens, CDCell MembraneCell MovementCytosolEndosomesHEK293 CellsHumansProtein TransportReceptors, TransferrinSubtilisinsTranscription Factor AP-2trans-Golgi NetworkAntigens, CDCD71 antigenproprotein convertase PC7Receptors, TransferrinSubtilisinsTranscription Factor AP-2adaptor protein 2 (AP-2)cell sortingconvertasecytosolic tail (CT)proprotein convertase type 7proteaseprotein dynamicsheddingtraffickingtransferrin receptor 1(TfR1)

Identifiers

PMID31915245
PMCPMC7029121
OpenAlexW3000572934

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.