Evidence map›Paper›PMID 31915223›Full record

ArticlemSphere2020

Influence of Plasmodium falciparum Calcium-Dependent Protein Kinase 5 (PfCDPK5) on the Late Schizont Stage Phosphoproteome.

Karin Blomqvist, Michaela Helmel, Chengqi Wang, Sabrina Absalon, Tetanya Labunska, Rachel M Rudlaff, Swamy Adapa, Rays Jiang, Hanno Steen, Jeffrey D Dvorin

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

  1. The essential function of the apical polar ring during the blood stage ofbioRxiv : the preprint server for biology · 2026
    Article
  2. Review
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  11. CaScience advances · 2021
    Article
  12. Calcium in the Backstage of Malaria Parasite Biology.Frontiers in cellular and infection microbiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Karin BlomqvistDivision of Infectious Diseases, Boston Children's Hospital, Boston, Massachusetts, USA.
Michaela HelmelDepartment of Pathology, Boston Children's Hospital, Boston, Massachusetts, USA.
Chengqi WangCenter for Global Health & Infectious Diseases Research, Department of Global Health, College of Public Health, University of South Florida, Tampa, Florida, USA.
Sabrina AbsalonDivision of Infectious Diseases, Boston Children's Hospital, Boston, Massachusetts, USA.
Tetanya LabunskaDivision of Infectious Diseases, Boston Children's Hospital, Boston, Massachusetts, USA.
Rachel M RudlaffDivision of Infectious Diseases, Boston Children's Hospital, Boston, Massachusetts, USA.
Swamy AdapaCenter for Global Health & Infectious Diseases Research, Department of Global Health, College of Public Health, University of South Florida, Tampa, Florida, USA.
Rays JiangCenter for Global Health & Infectious Diseases Research, Department of Global Health, College of Public Health, University of South Florida, Tampa, Florida, USA.
Hanno SteenDepartment of Pathology, Boston Children's Hospital, Boston, Massachusetts, USA.
Jeffrey D DvorinDivision of Infectious Diseases, Boston Children's Hospital, Boston, Massachusetts, USA jeffrey.dvorin@childrens.harvard.edu.ORCID 0000-0002-5883-7271
Boston Children's Hospital · USUniversity of South Florida · US

Funding

Molecular mechanisms of schizogony in malaria parasitesR01AI145941 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI DVORIN, JEFFREY D · 2019 to 2023
$3.1M
Molecular characterization and substrate identification of malaria kinase PfCDPK5R01AI102907 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI DVORIN, JEFFREY D · 2014 to 2017
$1.8M
NIAID NIH HHS R01 AI102907NIAID NIH HHS R01 AI145941
6 · The paper itself

Abstract

Protein kinases are important mediators of signal transduction in cellular pathways, and calcium-dependent protein kinases (CDPKs) compose a unique class of calcium-dependent kinases present in plants and apicomplexans, including

Indexed as

Calcium-Binding ProteinsCell MembraneGene OntologyPhosphoproteinsPhosphorylationPlasmodium falciparumProtein KinasesProteomeProtozoan ProteinsSchizontsSignal TransductionCalcium-Binding ProteinsCDPK5 protein, Plasmodium falciparumPhosphoproteinsProtein KinasesProteomeProtozoan Proteinscalcium-dependent protein kinasemalariaphosphoproteomePlasmodium falciparum

Identifiers

PMID31915223
PMCPMC6952208
OpenAlexW2999369584

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.