Evidence map›Paper›PMID 31915207›Full record

ArticleJournal of neurointerventional surgery2020

Long-term functional outcome following minimally invasive endoscopic intracerebral hemorrhage evacuation.

Christopher P Kellner, Rui Song, Jonathan Pan, Dominic A Nistal, Jacopo Scaggiante, Alexander G Chartrain, Jamie Rumsey, Danny Hom, Neha Dangayach, Rupendra Swarup and 4 more

2 registry-linked trialsAbstract read
In one paragraph

Article in Journal of neurointerventional surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05538286 narecruitingnot on this mapstarted 2022, after this paper: background citation

Transcranial Ultrasound Via Sonolucent Cranioplasty After Minimally Invasive Intracerebral Hemorrhage Evacuation

TypeinterventionalSponsorIcahn School of Medicine at Mount SinaiRan2022 to 2027Enrolled25ConditionsTranscranial Ultrasound With Sonolucent Cranioplasty, TUSCArmsClearFit implant, transcranial ultrasonography through sonolucent cranioplasty
NCT05539859 narecruitingnot on this mapstarted 2022, after this paper: background citation

Efficacy and Safety of NeuroEndoscopic Surgery for IntraCerebral Hemorrhage: a Randomised, Controlled, Open-label, Blinded Endpoint Trial

TypeinterventionalSponsorSouthwest Hospital, ChinaRan2022 to 2026Enrolled560ConditionsIntracerebral Hemorrhage Basal GangliaArmsEndoscopic surgery, Medical management
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  15. Purely Endoscopic Evacuation of Intracranial Hematomas.Advances and technical standards in neurosurgery · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Rui SongDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.
Jonathan PanDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.
Dominic A NistalDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.ORCID http://orcid.org/0000-0001-9713-5873
Jacopo ScaggianteDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.
Alexander G ChartrainDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.
Jamie RumseyDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.
Danny HomDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.
Neha DangayachDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.
Rupendra SwarupDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.
Stanley TuhrimDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.
Saadi GhatanDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.
Joshua B BedersonDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.
J MoccoDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposePreclinical studies suggest that clot removal may mitigate primary and secondary brain injury following intracerebral hemorrhage (ICH). Although the MISTIE trial did not demonstrate an overall outcome benefit, it did demonstrate outcome benefit from effective reduction of clot burden. Minimally invasive endoscopic ICH evacuation may provide an alternative option for clot evacuation.

methodsPatients presenting to a single healthcare system from December 2015 to October 2018 with supratentorial spontaneous ICH were evaluated for minimally invasive endoscopic evacuation. Inclusion and exclusion criteria were prospectively established by a multidisciplinary group in the healthcare system. The prespecified primary analysis was the proportion of patients with modified Rankin Score (mRS) 0-3 at 6 months.

resultsOne hundred patients met the inclusion and exclusion criteria and underwent minimally invasive endoscopic ICH evacuation. The mean (SD) hematoma size was 49.7 (30.6) mL, the mean (SD) evacuation percentage was 88.2 (20.3)%, and 86% of patients had postoperative residual hematoma ≤15 mL. At 6 months the proportion of patients with an mRS of 0-3 was 46%.

conclusionsThis study suggests that minimally invasive endoscopic ICH evacuation may produce favorable long-term functional outcomes. Further evaluation of this technique in a randomized clinical trial is necessary.

Indexed as

AdultAgedCerebral HemorrhageFemaleHematomaHumansMaleMiddle AgedMinimally Invasive Surgical ProceduresNeuroendoscopyRetrospective StudiesTime FactorsTreatment Outcomeendoscopicimage-guideintracerebral hemorrhageminimally invasive

Identifiers

PMID31915207
PMCPMC7231458

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.