ArticleBMJ (Clinical research ed.)2020
Healthy lifestyle and life expectancy free of cancer, cardiovascular disease, and type 2 diabetes: prospective cohort study.
Article in BMJ (Clinical research ed.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 346 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Development and Implementation of a Tool for the Evaluation and Monitorization of Mediterranean Lifestyle at Clinical Settings: MEDLIFE Index, a Proof of Concept Study
Environment, Inflammation and Metabolic Diseases Study
Who cites it
346 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Pooled it
- Pooled it
- Combination of Multiple Low-Risk Lifestyle Behaviors and Incident Type 2 Diabetes: A Systematic Review and Dose-Response Meta-analysis of Prospective Cohort Studies.Diabetes care · 2023Pooled it
- Effectiveness of the Components of a Digital Multiple Health Behavior Intervention Among University Students (Buddy): Factorial Randomized Trial.Journal of medical Internet research · 2026Trial
- Healthy lifestyle factors and recurrent cardiovascular events in patients with OSA: the SAVE study.BMC medicine · 2025Trial
- Mass spectrometry-detected MGUS is associated with obesity and other novel modifiable risk factors in a high-risk population.Blood advances · 2024Trial
- Meeting lifestyle recommendations among cancer survivors - a cross-sectional descriptive analysis from the Swedish CArdioPulmonary BioImage study (SCAPIS).Journal of cancer survivorship : research and practice · 2026Article
- Maternal lifestyle risk factors and human embryonic morphologic development using 3D ultrasound: a population-based prospective cohort study.Human reproduction (Oxford, England) · 2026Article
- Healthy lifestyle attenuates the clonal hematopoiesis-associated coronary artery disease risk.Fundamental research · 2026Article
- Healthy Lifestyle Behaviors and Technostress: A Combined Lifestyle Score Analysis in 104,175 Spanish Workers.Nutrients · 2026Article
- Associations of loneliness, social isolation and healthy lifestyle with life expectancy free of major physical disease and mental disorder.Nature communications · 2026Article
- A Lifestyle Behavior Score Predicting Cardiovascular and Other Causes of Death in a Cohort of Middle-Aged Men Followed up Until Extinction.Journal of cardiovascular development and disease · 2026Article
- Examining the clustering of lifestyle factors and affect in daily life: An idiographic approach.Applied psychology. Health and well-being · 2026Article
- The mediating role of healthy lifestyle in the association between higher socioeconomic status and an increased risk of allergic rhinitis: an analysis of NHANES.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Review
- Estimation of biological age and age-related outcomes with easily accessible parameters in Chinese.GeroScience · 2026Article
- Impact of a comprehensive healthy lifestyle and genetic risk on arrhythmia: insights from the UK biobank study.BMC cardiovascular disorders · 2026Article
- Decline and Resurgence of Cardiovascular-Kidney-Metabolic Syndrome-Related Deaths Involving Malnutrition in the United States, 1999 to 2023.Journal of the American Heart Association · 2026Article
- Long-term resistance training with all-cause and cause-specific mortality: assessing dose-response and joint associations with aerobic physical activity.British journal of sports medicine · 2026Article
- Variable selection-combined causal mediation analysis for continuous treatments with application to large-dimensional biomedical data.PLoS computational biology · 2026Article
286 more citing papers are in PubMed but not listed here.
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Authors and funding
18 authors.
Funding
Abstract
objectiveTo examine how a healthy lifestyle is related to life expectancy that is free from major chronic diseases.
designProspective cohort study. SETTING AND
participantsThe Nurses' Health Study (1980-2014; n=73 196) and the Health Professionals Follow-Up Study (1986-2014; n=38 366). MAIN EXPOSURES: Five low risk lifestyle factors: never smoking, body mass index 18.5-24.9, moderate to vigorous physical activity (≥30 minutes/day), moderate alcohol intake (women: 5-15 g/day; men 5-30 g/day), and a higher diet quality score (upper 40%). MAIN OUTCOME: Life expectancy free of diabetes, cardiovascular diseases, and cancer.
resultsThe life expectancy free of diabetes, cardiovascular diseases, and cancer at age 50 was 23.7 years (95% confidence interval 22.6 to 24.7) for women who adopted no low risk lifestyle factors, in contrast to 34.4 years (33.1 to 35.5) for women who adopted four or five low risk factors. At age 50, the life expectancy free of any of these chronic diseases was 23.5 (22.3 to 24.7) years among men who adopted no low risk lifestyle factors and 31.1 (29.5 to 32.5) years in men who adopted four or five low risk lifestyle factors. For current male smokers who smoked heavily (≥15 cigarettes/day) or obese men and women (body mass index ≥30), their disease-free life expectancies accounted for the lowest proportion (≤75%) of total life expectancy at age 50.
conclusionAdherence to a healthy lifestyle at mid-life is associated with a longer life expectancy free of major chronic diseases.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.