ArticleImplementation science : IS2020
Unpacking the complexities of de-implementing inappropriate health interventions.
Article in Implementation science : IS, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 166 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
166 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Stakeholders' perceptions and experiences of factors influencing the commissioning, delivery, and uptake of general health checks: a qualitative evidence synthesis.The Cochrane database of systematic reviews · 2025Pooled it
- A systematic review of experimentally tested implementation strategies across health and human service settings: evidence from 2010-2022.Implementation science : IS · 2024Pooled it
- Built to last? Barriers and facilitators of healthcare program sustainability: a systematic integrative review.Implementation science : IS · 2023Pooled it
- Interventions for preventing and reducing the use of physical restraints for older people in all long-term care settings.The Cochrane database of systematic reviews · 2023Pooled it
- Implementation of Evidence-Based Practices within Treatment-As-Usual and Evidence-Based Practice Initiatives.Administration and policy in mental health · 2022Pooled it
- De-implementing low-value care in cancer care delivery: a systematic review.Implementation science : IS · 2022Pooled it
- Effects of de-implementation strategies aimed at reducing low-value nursing procedures: a systematic review and meta-analysis.Implementation science : IS · 2020Pooled it
- Balanced informational feedback as part of an implementation/deimplementation bundle to support deimplementation efforts in antimicrobial stewardship: results from a mixed methods, hybrid type III implementation/effectiveness trial.Frontiers in public health · 2026Trial
- Strategies to Deimplement Opioid Prescribing in Primary Care: A Cluster Randomized Clinical Trial.JAMA network open · 2024Trial
- Shared Decision-Making in Colorectal Cancer Screening for Older Adults: A Secondary Analysis of a Cluster Randomized Clinical Trial.JAMA network open · 2024Trial
- Ethical Aspects of Physician Decision-Making for Deprescribing Among Older Adults With Dementia.JAMA network open · 2023Trial
- De-Implementing Opioids for Dental Extractions (DIODE): a multi-clinic, cluster-randomized trial of clinical decision support strategies in dentistry.Implementation science : IS · 2023Trial
- Interruptive Electronic Alerts for Choosing Wisely Recommendations: A Cluster Randomized Controlled Trial.Journal of the American Medical Informatics Association : JAMIA · 2022Trial
- Pragmatic Trials in Long-Term Care: Research Challenges and Potential Solutions in Relation to Key Areas of Care.Journal of the American Medical Directors Association · 2022Trial
- A cluster randomized stepped-wedge trial to de-implement unnecessary post-operative antibiotics in children: the optimizing perioperative antibiotic in children (OPerAtiC) trial.Implementation science : IS · 2021Trial
- Effect of Clinical Decision Support on Diagnostic Imaging for Pediatric Appendicitis: A Cluster Randomized Trial.JAMA network open · 2021Trial
- Design and method considerations for equity-centered implementation science and practice: A PEDALs approach.Global health research and policy · 2026Article
- Global under- and overprescribing of drugs-a scoping review.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- When is AI "just another innovation"? A comparative conceptual analysis of artificial intelligence and evidence-based practice implementation.Implementation science communications · 2026Article
- Habit Formation to Enhance Implementation of Evidence-based Practice.Administration and policy in mental health · 2026Review
106 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
De-implementing inappropriate health interventions is essential for minimizing patient harm, maximizing efficient use of resources, and improving population health. Research on de-implementation has expanded in recent years as it cuts across types of interventions, patient populations, health conditions, and delivery settings. This commentary explores unique aspects of de-implementing inappropriate interventions that differentiate it from implementing evidence-based interventions, including multi-level factors, types of action, strategies for de-implementation, outcomes, and unintended negative consequences. We highlight opportunities to continue to advance research on the de-implementation of inappropriate interventions in health care and public health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.