Evidence map›Paper›PMID 31914918›Full record

ArticleBMC microbiology2020

Evaluation of resazurin-based assay for rapid detection of polymyxin-resistant gram-negative bacteria.

Huaiyu Jia, Renchi Fang, Jie Lin, Xuebin Tian, Yajie Zhao, Lijiang Chen, Jianming Cao, Tieli Zhou

Open access · goldAbstract read
In one paragraph

Article in BMC microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Rapid ResaCeftazidime-AvibactamJournal of clinical microbiology · 2022
    Article
  9. Article
  10. RapidResa PolymyxinAntibiotics (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Huaiyu JiaDepartment of Clinical Laboratory, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang province, China.
Renchi FangDepartment of Clinical Laboratory, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang province, China.
Jie LinDepartment of Clinical Laboratory, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang province, China.
Xuebin TianSchool of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Yajie ZhaoSchool of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Lijiang ChenDepartment of Clinical Laboratory, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang province, China.
Jianming CaoSchool of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang Province, China. wzcjming@163.com.
Tieli ZhouDepartment of Clinical Laboratory, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang province, China. wyztli@163.com.ORCID 0000-0002-2171-4710
Wenzhou Medical University · CN

Funding

the General Scientific Research Project of the Education Department of Zhejiang Province of China No. Y201942210the National Natural Science Foundations of China No. 81971986the Planned Science and Technology Project of Wenzhou no. Y20170204
6 · The paper itself

Abstract

backgroundColistin resistance is considered a serious problem due to a lack of alternative antibiotics. The Rapid ResaPolymyxin Acinetobacter/Pseudomonas NP test is a resazurin reduction-based technique that relies on the visual detection of bacterial growth in the presence of a defined concentration of colistin. The aim of this study was to evaluate the performance of the Rapid ResaPolymyxin Acinetobacter/Pseudomonas NP test in the detection of colistin susceptibility in common clinical Gram-negative bacteria.

resultsA total of 253 clinical isolates from a teaching hospital, including Acinetobacter baumanii (n = 58, 8 colistin-resistant), Pseudomonas aeruginosa (n = 61, 11 colistin-resistant), Klebsiella pneumoniae (n = 70, 20 colistin-resistant) and Escherichia coli (n = 64, 14 colistin-resistant) were tested in this study. The sensitivity and specificity of the Rapid ResaPolymyxin Acinetobacter/Pseudomonas NP test compared to Broth microdilution method was 100 and 99%, respectively.

conclusionsOur results suggest that Rapid ResaPolymyxin Acinetobacter/Pseudomonas NP test could be used as an accurate detection method for colistin resistance.

Indexed as

Drug Resistance, BacterialAcinetobacter baumanniiDiagnostic Tests, RoutineGram-Negative BacteriaHospitals, TeachingKlebsiella pneumoniaeMicrobial Sensitivity TestsOxazinesPolymyxinsPseudomonas aeruginosaSensitivity and SpecificityXanthenesOxazinesPolymyxinsresazurinXanthenesColistin-resistantGram-negative bacteriaRapid diagnosisRapid ResaPolymyxin Acinetobacter/Pseudomonas NP test

Identifiers

PMID31914918
PMCPMC6950887
OpenAlexW3000239495

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.