Evidence map›Paper›PMID 31914841›Full record

ArticleInnate immunity2020

Extracellular ATP is a potent signaling molecule in the activation of the Japanese flounder (

Shuo Li, Xiaoli Chen, Jiafang Li, Xuejing Li, Tianxu Zhang, Gaixiang Hao, Jinsheng Sun

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Innate immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Animal Models for the Investigation of P2X7 Receptors.International journal of molecular sciences · 2023
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shuo LiTianjin Key Laboratory of Animal and Plant Resistance, Tianjin Normal University, China.
Xiaoli ChenTianjin Key Laboratory of Animal and Plant Resistance, Tianjin Normal University, China.
Jiafang LiTianjin Key Laboratory of Animal and Plant Resistance, Tianjin Normal University, China.
Xuejing LiTianjin Key Laboratory of Animal and Plant Resistance, Tianjin Normal University, China.
Tianxu ZhangTianjin Key Laboratory of Animal and Plant Resistance, Tianjin Normal University, China.
Gaixiang HaoTianjin Key Laboratory of Animal and Plant Resistance, Tianjin Normal University, China.
Jinsheng SunTianjin Key Laboratory of Animal and Plant Resistance, Tianjin Normal University, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Innate immunity is the first line of defense against pathogen infections. Extracellular ATP (eATP) is one of the most studied danger-associated molecular pattern molecules that can activate host innate immune responses through binding with and activating purinergic receptors on the plasma membrane. The detailed actions of eATP on fish innate immunity, however, remain poorly understood. In this study, we investigated bacterial pathogen-induced ATP release in head kidney cells of the Japanese flounder

Indexed as

Adenosine TriphosphateAnimalsAntigens, BacterialCells, CulturedCytokinesEdwardsiella tardaEnterobacteriaceae InfectionsExtracellular SpaceFish ProteinsFlounderHead KidneyImmunity, InnateInflammation MediatorsNitric Oxide Synthase Type IISignal TransductionUp-RegulationAdenosine TriphosphateAntigens, BacterialCytokinesFish ProteinsInflammation MediatorsNitric Oxide Synthase Type IIATP releaseExtracellular ATPinnate immune responseParalichthys olivaceusteleost

Identifiers

PMID31914841
PMCPMC7903527

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.