Evidence map›Paper›PMID 31914617›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2020

Membrane-type frizzled-related protein regulates lipidome and transcription for photoreceptor function.

Marie-Audrey I Kautzmann, William C Gordon, Bokkyoo Jun, Khanh V Do, Blake J Matherne, Zhide Fang, Nicolas G Bazan

Open access · hybridAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 28 citations in OpenAlex.

  1. Polyunsaturated fatty acid metabolism in the retinal pigment epithelium and its association with outer retinal disease.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
    Review
  2. Review
  3. Article
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  5. Article
  6. Article
  7. Frontiers in genetics · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Genetic Interaction betweenInternational journal of molecular sciences · 2022
    Article
  13. Article
  14. Review
  15. Article
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  17. Review
  18. Article
  19. Article
  20. Membrane-type frizzled-related protein regulates lipidome and transcription for photoreceptor function.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Marie-Audrey I KautzmannNeuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA, USA.
William C GordonNeuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA, USA.
Bokkyoo JunNeuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA, USA.
Khanh V DoNeuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA, USA.
Blake J MatherneNeuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA, USA.
Zhide FangBiostatistics, School of Public Health, Louisiana State University Health New Orleans, New Orleans, LA, USA.
Nicolas G BazanNeuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA, USA.
Louisiana State University Health Sciences Center New Orleans · US

Funding

RPE Messengers, Transcription &Photoreceptor RenewalR01EY005121 · NEI · LSU HEALTH SCIENCES CENTER · PI Nicolas G. Bazan · 1985 to 2026
$9.1M
Multiphoton ConfocalP30GM103340 · NIGMS · LSU HEALTH SCIENCES CENTER · PI SHELINE, CHRISTIAN THOMAS · 2012 to 2016
$5.1M
NEI NIH HHS R01 EY005121NIGMS NIH HHS P30 GM103340
6 · The paper itself

Abstract

Molecular decision-makers of photoreceptor (PRC) membrane organization and gene regulation are critical to understanding sight and retinal degenerations that lead to blindness. Using Mfrp

Indexed as

Gene Expression RegulationLipidomicsAnimalsCell MembraneElectroretinographyEye ProteinsFemaleFrizzled-Related ProteinsInflammationMaleMass SpectrometryMembrane ProteinsMiceMice, Inbred C57BLMice, KnockoutReceptors, Adiponectinadiponectin receptor 1, mouseEye ProteinsFrizzled-Related ProteinsMembrane ProteinsMfrp protein, mouseReceptors, AdiponectinAdipor1inflammatory signalingmatrix‐assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS)retinal degenerationsRPE cellVLC‐PUFAs

Identifiers

PMID31914617
PMCPMC6956729
OpenAlexW2989714274

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.