Evidence map›Paper›PMID 31914416›Full record

ArticleThe Journal of biological chemistry2020

Disruption of the dimerization interface of the sensing domain in the dimeric heme-based oxygen sensor

Tereza Skalova, Alzbeta Lengalova, Jan Dohnalek, Karl Harlos, Peter Mihalcin, Petr Kolenko, Martin Stranava, Jan Blaha, Toru Shimizu, Markéta Martínková

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Applications of the Whole-Cell System in the Efficient Biosynthesis of Heme.International journal of molecular sciences · 2023
    Review
  2. Article
  3. Article
  4. Article
  5. Structural modeling of a novel membrane-bound globin-coupled sensor inComputational and structural biotechnology journal · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Tereza SkalovaInstitute of Biotechnology of the Czech Academy of Sciences, v.v.i., Biocev, Vestec, 252 50 Czech Republic.
Alzbeta LengalovaDepartment of Biochemistry, Faculty of Science, Charles University, Prague 2, 128 43 Czech Republic.
Jan DohnalekInstitute of Biotechnology of the Czech Academy of Sciences, v.v.i., Biocev, Vestec, 252 50 Czech Republic.
Karl HarlosDivision of Structural Biology, The Wellcome Trust Centre for Human Genetics, University of Oxford, OX3 7BN Oxford, United Kingdom.
Peter MihalcinDepartment of Biochemistry, Faculty of Science, Charles University, Prague 2, 128 43 Czech Republic.
Petr KolenkoInstitute of Biotechnology of the Czech Academy of Sciences, v.v.i., Biocev, Vestec, 252 50 Czech Republic; FNSPE, Czech Technical University in Prague, Brehova 7, Prague 1, 115 19 Czech Republic.
Martin StranavaDepartment of Biochemistry, Faculty of Science, Charles University, Prague 2, 128 43 Czech Republic.
Jan BlahaDepartment of Biochemistry, Faculty of Science, Charles University, Prague 2, 128 43 Czech Republic.
Toru ShimizuDepartment of Biochemistry, Faculty of Science, Charles University, Prague 2, 128 43 Czech Republic.
Markéta MartínkováDepartment of Biochemistry, Faculty of Science, Charles University, Prague 2, 128 43 Czech Republic. Electronic address: marketa.martinkova@natur.cuni.cz.
Charles University · CZCzech Academy of Sciences, Institute of Biotechnology · CZCentre for Human Genetics · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

The heme-based oxygen sensor protein

Indexed as

Bacterial ProteinsCrystallography, X-RayGlobinsHistidine KinaseModels, MolecularMyxococcalesPhosphorylationProtein ConformationProtein Conformation, alpha-HelicalProtein DomainsProtein MultimerizationSignal TransductionBacterial ProteinsGlobinsHistidine Kinasebacterial protein kinasecell signalingcrystal structuredimerization interfaceglobinhemeheme-based oxygen sensorhistidine kinasesignal transductiontwo component system

Identifiers

PMID31914416
PMCPMC7008379
OpenAlexW2997652571

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.