Evidence map›Paper›PMID 31914017›Full record

Observational studyMedicine2020

Human growth hormone level decreased in women aged <60 years but increased in men aged >50 years.

Ximei Wang, Shuyi Wang, Huan Wu, Mingfei Jiang, Hui Xue, Yangqi Zhu, Chenxu Wang, Xiaojuan Zha, Yufeng Wen

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ximei WangSchool of Laboratory Medicine.
Shuyi WangSchool of Laboratory Medicine.
Huan WuSchool of Laboratory Medicine.
Mingfei JiangSchool of Laboratory Medicine.
Hui XueSchool of Public Health.
Yangqi ZhuSchool of Laboratory Medicine.
Chenxu WangSchool of Public Health.
Xiaojuan ZhaFirst Affiliated Hospital, Wannan Medical College, Wuhu City, Anhui Province, China.
Yufeng WenSchool of Laboratory Medicine.
Wannan Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate the relationship amongst human growth hormone (HGH), sex, and age groups.A cross-sectional study was conducted on a health check-up population from Wannan area of China from 2014 to 2016. The study involved 6843 individuals aged 23 to 85 years. Logistic regression analysis and smooth curve were applied to determine the relationship amongst age, sex, and HGH.The average level of HGH in the population was 0.37 ± 0.59 ng/mL. There were significant differences in sex, age, body mass index (BMI), triglycerides (TG), total cholesterol (TC), systolic blood pressure (SBP), diastolic blood pressure (DBP), and glucose (GLU) amongst different quartiles of HGH (P < .001). A U-shape relationship was established between HGH and age. After sex stratification, the results showed that the thresholds of age were 60 years in women, and 50 years in men, after adjusting for body mass index, triglycerides, total cholesterol, blood pressure, and blood glucose. Logistic regression showed that HGH level decreased in women aged <60 years (OR = 1.472, P < .001) and increased in men aged >50 years (OR = 0.711, P < .001). So the distributive characteristics of HGH concentration vary with sex and age group.

Indexed as

AdultAgedAged, 80 and overAge FactorsBlood PressureBody Mass IndexChinaCross-Sectional StudiesFemaleHuman Growth HormoneHumansMaleMiddle AgedSex FactorsTriglyceridesHuman Growth HormoneTriglycerides

Identifiers

PMID31914017
PMCPMC6959966
OpenAlexW2998936350

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.