Evidence map›Paper›PMID 31913767›Full record

ArticleEmerging microbes & infections2020

Seroreactivity against Marburg or related filoviruses in West and Central Africa.

Imke Steffen, Kai Lu, Nicole A Hoff, Prime Mulembakani, Emile Okitolonda Wemakoy, Jean-Jacques Muyembe-Tamfum, Nicaise Ndembi, Catherine A Brennan, John Hackett, William M Switzer and 5 more

Open access · goldAbstract readLetter
In one paragraph

Article in Emerging microbes & infections, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.2field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 11 institutions in 5 countries.

Imke SteffenVitalant Research Institute, San Francisco, CA, USA.
Kai LuVitalant Research Institute, San Francisco, CA, USA.
Nicole A HoffDepartment of Epidemiology, School of Public Health, University of California Los Angeles, Los Angeles, CA, USA.
Prime MulembakaniKinshasa School of Public Health, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Emile Okitolonda WemakoyKinshasa School of Public Health, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Jean-Jacques Muyembe-TamfumInstitut National de Recherche Biomedicale, Kinshasa, Democratic Republic of the Congo.
Nicaise NdembiInstitute of Human Virology, Abuja, Nigeria.
Catherine A BrennanAbbott Diagnostics, Abbott Park, IL, USA.
John HackettAbbott Diagnostics, Abbott Park, IL, USA.
William M SwitzerCenters for Disease Control and Prevention, Atlanta, GA, USA.
Sentob SaragostiINSERM U941, Paris, France.
Guy O MbensaCentre National de Transfusion Sanguine, Kinshasa, Democratic Republic of Congo.
Syria LapercheInstitut National de la Transfusion Sanguine, Paris, France.
Anne W RimoinDepartment of Epidemiology, School of Public Health, University of California Los Angeles, Los Angeles, CA, USA.
Graham SimmonsVitalant Research Institute, San Francisco, CA, USA.
Abbott (Germany) · DEInstitut National de la Transfusion Sanguine · FRUniversity of California, San Francisco · USUniversity of Kinshasa · CDCenters for Disease Control and Prevention · USInserm · FRInstitute of Human Virology · NGLos Angeles County Department of Public Health · USNational Institute of Biomedical Research · CDPacific Research Institute · USUniversity of California, Los Angeles · US

Funding

Serological prevalence of viral hemorrhagic fevers in Equatorial AfricaR21AI107420 · NIAID · VITALANT · PI SIMMONS, GRAHAM · 2014 to 2015
$438k
NIAID NIH HHS R21 AI107420
6 · The paper itself

Abstract

A serological survey of 2,430 archived serum samples collected between 1997 and 2012 was conducted to retrospectively determine the prevalence of Marburg virus in five African countries. Serum samples were screened for neutralizing antibodies in a pseudotype micro-neutralization assay and confirmed by enzyme-linked immunosorbent assay (ELISA). Surprisingly, a seroprevalence for Marburg virus of 7.5 and 6.3% was found in Cameroon and Ghana, respectively, suggesting the circulation of filoviruses or related viruses outside of known endemic areas that remain undetected by current surveillance efforts. However, due to the lack of validated assays and appropriate positive controls, these results must be considered preliminary.

Indexed as

AnimalsAntibodies, ViralCameroonEnzyme-Linked Immunosorbent AssayFiloviridaeFiloviridae InfectionsGhanaHumansMarburgvirusMarburg Virus DiseaseRetrospective StudiesSeroepidemiologic StudiesAntibodies, ViralCameroonFilovirusesGhanahemorrhagic fever virusMarburgvirusprevalenceserology

Identifiers

PMID31913767
PMCPMC6968259
OpenAlexW3000520763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.