Evidence map›Paper›PMID 31913686›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2020

Muscle sympathetic reactivity to apneic and exercise stress in high-altitude Sherpa.

Stephen A Busch, Lydia L Simpson, Frances Sobierajski, Laurel Riske, Philip N Ainslie, Chris K Willie, Mike Stembridge, Jonathan P Moore, Craig D Steinback

Abstract read
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Autonomic cardiovascular control during exercise.American journal of physiology. Heart and circulatory physiology · 2023
    Review
  4. Adrenergic control of skeletal muscle blood flow during chronic hypoxia in healthy males.American journal of physiology. Regulatory, integrative and comparative physiology · 2023
    Article
  5. Greater resting muscle sympathetic nerve activity reduces cold pressor autonomic reactivity in older women, but not older men.American journal of physiology. Regulatory, integrative and comparative physiology · 2023
    Article
  6. Article
  7. Review
  8. Article
  9. The potential role of the carotid body in COVID-19.American journal of physiology. Lung cellular and molecular physiology · 2020
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Stephen A BuschNeurovascular Health Lab, Faculty of Kinesiology, Sport, and Recreation, University of Alberta, Edmonton, Alberta, Canada.
Lydia L SimpsonSchool of Sport, Health, and Exercise Sciences, Bangor University, Bangor, United Kingdom.
Frances SobierajskiNeurovascular Health Lab, Faculty of Kinesiology, Sport, and Recreation, University of Alberta, Edmonton, Alberta, Canada.
Laurel RiskeNeurovascular Health Lab, Faculty of Kinesiology, Sport, and Recreation, University of Alberta, Edmonton, Alberta, Canada.
Philip N AinslieCentre for Heart, Lung, and Vascular Health, University of British Columbia Okanagan, Kelowna, British Columbia, Canada.
Chris K WillieCentre for Heart, Lung, and Vascular Health, University of British Columbia Okanagan, Kelowna, British Columbia, Canada.
Mike StembridgeCardiff Centre for Exercise and Health, Cardiff School of Sport and Health, Cardiff Metropolitan University, Cardiff, United Kingdom.
Jonathan P MooreSchool of Sport, Health, and Exercise Sciences, Bangor University, Bangor, United Kingdom.ORCID 0000-0002-4244-8220
Craig D SteinbackNeurovascular Health Lab, Faculty of Kinesiology, Sport, and Recreation, University of Alberta, Edmonton, Alberta, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lowland-dwelling populations exhibit persistent sympathetic hyperactivity at altitude that alters vascular function. High-altitude populations, such as Sherpa, have previously exhibited greater peripheral blood flow in response to acute stress than Lowlanders, which may be explained through lower sympathetic activity. Our purpose was to determine whether Sherpa exhibit lower sympathetic reactivity to stress than Lowlanders. Muscle sympathetic nerve activity (MSNA; microneurography) was measured at rest in Lowlanders (

Indexed as

AltitudeAdaptation, PhysiologicalAdultExerciseFemaleHand StrengthHeart RateHumansMaleMuscle, SkeletalSympathetic Nervous SystemaltitudeapneahypoxiametabolismSherpa

Identifiers

PMID31913686
PMCPMC7099458

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.