Evidence map›Paper›PMID 31913553›Full record

ArticlePhysiotherapy research international : the journal for researchers and clinicians in physical therapy2020

Aerobic capacity is associated with disease activity and cardiovascular risk factors in early rheumatoid arthritis.

Lars Ångström, Kristina Hörnberg, Björn Sundström, Solveig Wållberg Jonsson, Anna Södergren

Open access · bronzeAbstract read
In one paragraph

Article in Physiotherapy research international : the journal for researchers and clinicians in physical therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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  8. Aerobic capacity is associated with disease activity and cardiovascular risk factors in early rheumatoid arthritis.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lars ÅngströmDepartment of Public Health and Clinical Medicine/Rheumatology, Umeå University, Umeå, Sweden.ORCID https://orcid.org/0000-0002-0839-9146
Kristina HörnbergDepartment of Public Health and Clinical Medicine/Rheumatology, Umeå University, Umeå, Sweden.
Björn SundströmDepartment of Public Health and Clinical Medicine/Rheumatology, Umeå University, Umeå, Sweden.
Solveig Wållberg JonssonDepartment of Public Health and Clinical Medicine/Rheumatology, Umeå University, Umeå, Sweden.
Anna SödergrenDepartment of Public Health and Clinical Medicine/Rheumatology, Umeå University, Umeå, Sweden.
Umeå University · SE

Funding

Karolinska InstituteKing Gustaf V´s 80-year Fund, SwedenNorthern County CouncilsSvenska Sällskapet för Medicinsk ForskningSwedish Heart-Lung FoundationSwedish Rheumatism AssociationSwedish Rheumatism Association in the Västerbotten County;Swedish Society for Medical ResearchVisare Norr
6 · The paper itself

Abstract

objectivesThe aim of this study was to investigate aerobic capacity and its associations with disease activity and risk factors for cardiovascular disease (CVD) in early rheumatoid arthritis (RA).

methodsThis cross-sectional study included 67 patients with early RA. Aerobic capacity was estimated with the Åstrand submaximal test adjusted according to the Nord-Tröndelag Health Study formula. The following were also assessed: subclinical atherosclerosis by carotid intima-media thickness and pulse wave analysis; body composition by dual X-ray absorptiometry; estimated CVD mortality risk by the Systematic Coronary Risk Evaluation; disease activity by the Disease Activity Score 28, C-reactive protein and erythrocyte sedimentation rate; blood lipids by total cholesterol, low-density lipoproteins, high-density lipoproteins, and triglycerides; and functional ability by the Stanford health assessment questionnaire. Univariate and multiple linear regression analyses were performed to explore the associations between variables.

resultsThe mean (SD) aerobic capacity was 31.6 (8.7) ml O

conclusionsDisease activity and risk factors for CVD were in favour for patients with a higher aerobic capacity. Aerobic capacity was associated with disease activity and several risk factors for CVD, independent of age and sex. In RA, these findings may provide insights into the benefits of using aerobic capacity as a marker to prevent CVD.

Indexed as

Exercise ToleranceHeart Disease Risk FactorsAdultArthritis, RheumatoidAtherosclerosisBiomarkersCarotid Intima-Media ThicknessCross-Sectional StudiesFemaleHumansMaleMiddle AgedRisk FactorsBiomarkersaerobic capacitycardiovascular diseasedisease activityrheumatoid arthritis

Identifiers

PMID31913553
PMCPMC7378948
OpenAlexW3000356943

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.