Evidence map›Paper›PMID 31913411›Full record

Observational studyJAMA cardiology2020

Temporal Trends in Racial Differences in 30-Day Readmission and Mortality Rates After Acute Myocardial Infarction Among Medicare Beneficiaries.

Ambarish Pandey, Neil Keshvani, Rohan Khera, Di Lu, Muthiah Vaduganathan, Karen E Joynt Maddox, Sandeep R Das, Dharam J Kumbhani, Abhinav Goyal, Saket Girotra and 5 more

Open access · bronzeAbstract readComparative StudyObservational Study
In one paragraph

Observational study in JAMA cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 1 country.

Ambarish PandeyDivision of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas.
Neil KeshvaniDivision of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas.
Rohan KheraDivision of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas.
Di LuDuke Clinical Research Institute, Durham, North Carolina.
Muthiah VaduganathanBrigham and Women's Hospital Heart and Vascular Center, Harvard Medical School, Boston, Massachusetts.
Karen E Joynt MaddoxCardiovascular Division, Department of Medicine, Washington University School of Medicine in St Louis, St Louis, Missouri.
Sandeep R DasDivision of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas.
Dharam J KumbhaniDivision of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas.
Abhinav GoyalDivision of Cardiology, Emory University School of Medicine, Atlanta, Georgia.
Saket GirotraDivision of Cardiology, Department of Internal Medicine, University of Iowa, Iowa City.
Paul ChanMid America Heart Institute, Kansas City, Kansas City, Missouri.
Gregg C FonarowAhmanson-UCLA Cardiomyopathy Center, Ronald Reagan UCLA Medical Center, University of California, Los Angeles, Los Angeles.
Roland MatsouakaDuke Clinical Research Institute, Durham, North Carolina.
Tracy Y WangDuke Clinical Research Institute, Duke University, Durham, North Carolina.
James A de LemosDivision of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas.
The University of Texas Southwestern Medical Center · USClinical Research Institute · USBrigham and Women's Hospital · USEmory University · USRonald Reagan UCLA Medical Center · USUniversity of Iowa · USUniversity of Missouri–Kansas City · USWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Importance: The association of the Hospital Readmission Reduction Program (HRRP) with reductions in racial disparities in 30-day outcomes for myocardial infarction (MI), is unknown, including whether this varies by HRRP hospital penalty status. Objective: To assess temporal trends in 30-day readmission and mortality rates among black and nonblack patients discharged after hospitalization for acute MI at low-performing and high-performing hospitals, as defined by readmission penalty status after HRRP implementation. Design, Setting, and Participants: This observational cohort analysis used data from the multicenter National Cardiovascular Data Registry Chest Pain-MI Registry centers that were subject to the first cycle of HRRP, between January 1, 2008, and November 30, 2016. All patients hospitalized with MI who were included in National Cardiovascular Data Registry Chest Pain-MI Registry were included in the analysis. Data were analyzed from April 2018 to September 2019. Exposures: Hospital performance category and race (black compared with nonblack patients). Centers were classified as high performing or low performing based on the excess readmission ratio (predicted to expected 30-day risk adjusted readmission rate) for MI during the first HRRP cycle (in October 2012). Main Outcomes and Measures: Thirty-day all-cause readmission and mortality rates. Results: Among 753 hospitals that treated 155 397 patients with acute MI (of whom 11 280 [7.3%] were black), 399 hospitals (53.0%) were high performing. Thirty-day readmission rates declined over time in both black and nonblack patients (annualized 30-day readmission rate: 17.9% vs 20.8%). Black (compared with nonblack) race was associated with higher unadjusted odds of 30-day readmission in both low-performing and high-performing centers (odds ratios: before HRRP: low-performing hospitals, 1.14 [95% CI, 1.03-1.26]; P = .01; high-performing hospitals, 1.17 [95% CI, 1.04-1.32]; P = .01; after HRRP: low-performing hospitals, 1.23 [95% CI, 1.13-1.34]; P < .001; high-performing hospitals, 1.25 [95% CI, 1.12-1.39]; P < .001). However, these racial differences were not significant after adjustment for patient characteristics. The 30-day mortality rates declined significantly over time in nonblack patients, with stable (nonsignificant) temporal trends among black patients. Adjusted associations between race and 30-day mortality showed that 30-day mortality rates were significantly lower among black (compared with nonblack) patients in the low-performing hospitals (odds ratios: pre-HRRP, 0.79 [95% CI, 0.63-0.97]; P = .03; post-HRRP, 0.80 [95% CI, 0.68-0.95]; P = .01) but not in high-performing hospitals. Finally, the association between race and 30-day outcomes did not vary after the HRRP period began in either high-performing or low-performing hospitals. Conclusions and Relevance: In this analysis, 30-day readmission rates among patients with MI declined over time for both black and nonblack patients. Differences in race-specific 30-day readmission rates persisted but appeared to be attributable to patient-level factors. The 30-day mortality rates have declined for nonblack patients and remained stable among black patients. Implementation of the HRRP was not associated with improvement or worsening of racial disparities in readmission and mortality rates.

Indexed as

AgedAged, 80 and overBlack or African AmericanCohort StudiesFemaleHealthcare DisparitiesHumansMaleMedicareMyocardial InfarctionPatient ReadmissionRacial GroupsTime FactorsUnited States

Identifiers

PMID31913411
PMCPMC6990949
OpenAlexW3000597150

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.