Evidence map›Paper›PMID 31913325›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2020

Impact of erythrocyte long-chain omega-3 polyunsaturated fatty acid levels in early pregnancy on birth outcomes: findings from a Belgian cohort study.

Axelle Hoge, Anne-Françoise Donneau, Nadia Dardenne, Sylvie Degée, Marie Timmermans, Michelle Nisolle, Michèle Guillaume, Vincenzo Castronovo

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Article in Journal of perinatology : official journal of the California Perinatal Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Axelle HogeDepartment of Public Health, University of Liège, Liège, Belgium. axelle.hoge@uliege.be.
Anne-Françoise DonneauDepartment of Public Health, University of Liège, Liège, Belgium.
Nadia DardenneDepartment of Public Health, University of Liège, Liège, Belgium.
Sylvie DegéeDepartment of Obstetrics and Gynecology, CHR Citadelle Hospital, University of Liège, Liège, Belgium.
Marie TimmermansDepartment of Obstetrics and Gynecology, CHR Citadelle Hospital, University of Liège, Liège, Belgium.
Michelle NisolleDepartment of Obstetrics and Gynecology, CHR Citadelle Hospital, University of Liège, Liège, Belgium.
Michèle GuillaumeDepartment of Public Health, University of Liège, Liège, Belgium.
Vincenzo CastronovoMetastasis Research Laboratory, GIGA-CANCER, University of Liège, Liège, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine the association between maternal erythrocyte long-chain omega-3 PUFA (n-3 LCPUFA), measured in early pregnancy, and pregnancy and birth outcomes. STUDY

designOne hundred and eight healthy women with a singleton pregnancy were included. Erythrocyte fatty acids were analyzed using gas chromatography. Gestational length, birth anthropometric measures, and pregnancy-associated complications were collected from hospital medical records.

resultsWe observed significant positive associations between maternal docosahexaenoic acid (DHA) levels (p = 0.024) and omega-3 index values (p = 0.021) and gestational length in adjusted linear regression models. Each point in maternal DHA level was associated with 2.19 days longer gestational duration (β = 2.19; 95% CI 0.29-4.09). No consistent associations were found between n-3 PUFA levels and composite pregnancy outcome.

conclusionThese findings suggest that the gestational length is positively affected by maternal n-3 LCPUFA status as soon as the early stages of pregnancy.

Indexed as

Pregnancy OutcomeAdultBelgiumCohort StudiesDocosahexaenoic AcidsFatty Acids, Omega-3FemaleGestational AgeHumansInfant, NewbornLinear ModelsLogistic ModelsPregnancyPregnancy ComplicationsPregnancy Trimester, FirstPregnancy Trimester, SecondDocosahexaenoic AcidsFatty Acids, Omega-3

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.