ArticleNature communications2020
Symbiont population control by host-symbiont metabolic interaction in Symbiodiniaceae-cnidarian associations.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
54 citing papers in PubMed, 154 citations in OpenAlex.
- Advancing Symbiodiniaceae Functional Ecology Through a Trait-Based Framework.Ecology and evolution · 2026Review
- Seasonal Physiological Strategies Reveal Contrasting Host-Symbiont Dynamics Among Dominant Indo-Pacific Reef-Building Corals.Ecology and evolution · 2026Article
- Dual urea utilization enzyme systems in Symbiodiniaceae coral symbionts under warming.BMC biology · 2026Article
- Function and Development of Deep-sea Mussel Bacteriocytes Revealed by snRNA-seq and Spatial Transcriptomics.Genomics, proteomics & bioinformatics · 2026Article
- Heterotrophy and symbiosis affect energy reserves for pedal lacerates in the sea anemonePeerJ · 2026Article
- How to upgrade stolen organelles into permanent plastids: A comparative transcriptomic perspective.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Positive Selection of a Starch Synthesis Gene and Phenotypic Differentiation of Starch Accumulation in Symbiotic and Free-Living Coral Symbiont Dinoflagellate Species.Genome biology and evolution · 2025Article
- Stability of the cnidarian-dinoflagellate symbiosis is primarily determined by symbiont cell-cycle arrest.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Nitrogen source type modulates heat stress response in coral symbiont (Applied and environmental microbiology · 2025Article
- Destabilization of mutualistic interactions shapes the early heat stress response of the coral holobiont.Microbiome · 2025Article
- Distinct transcriptomic strategies underlie differential heat tolerance in Symbiodiniaceae symbionts.The ISME journal · 2025Article
- Cell type-specific immune regulation under symbiosis in a facultatively symbiotic coral.The ISME journal · 2025Article
- Article
- Coral larvae increase nitrogen assimilation to stabilize algal symbiosis and combat bleaching under increased temperature.PLoS biology · 2024Article
- Trade-off between photosymbiosis and innate immunity influences cnidarian's response to pathogenic bacteria.Proceedings. Biological sciences · 2024Article
- The genome of a giant clam zooxanthella (Cladocopium infistulum) offers few clues to adaptation as an extracellular symbiont with high thermotolerance.BMC genomics · 2024Article
- Article
- Genomes of the Caribbean reef-building coralsbioRxiv : the preprint server for biology · 2024Article
- Whole-genome duplication in an algal symbiont bolsters coral heat tolerance.Science advances · 2024Article
- Coordinated wound responses in a regenerative animal-algal holobiont.Nature communications · 2024Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In cnidarian-Symbiodiniaceae symbioses, algal endosymbiont population control within the host is needed to sustain a symbiotic relationship. However, the molecular mechanisms that underlie such population control are unclear. Here we show that a cnidarian host uses nitrogen limitation as a primary mechanism to control endosymbiont populations. Nitrogen acquisition and assimilation transcripts become elevated in symbiotic Breviolum minutum algae as they reach high-densities within the sea anemone host Exaiptasia pallida. These same transcripts increase in free-living algae deprived of nitrogen. Symbiotic algae also have an elevated carbon-to-nitrogen ratio and shift metabolism towards scavenging nitrogen from purines relative to free-living algae. Exaiptasia glutamine synthetase and glutamate synthase transcripts concomitantly increase with the algal endosymbiont population, suggesting an increased ability of the host to assimilate ammonium. These results suggest algal growth and replication in hospite is controlled by access to nitrogen, which becomes limiting for the algae as their population within the host increases.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.