Evidence map›Paper›PMID 31913138›Full record

ArticleDevelopmental period medicine2019

Do drugs used in obstetric anesthesia interfere with early breastfeeding? What determines drug safety in lactation? Part 1.

Maria Wilińska, Wojciech Walas, Ewa Kamińska, Małgorzata Malec Milewska, Agnieszka Sękowska, Ewa Helwich

Open access · greenAbstract read
In one paragraph

Article in Developmental period medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Maria WilińskaDepartment for Neonatology, Prof. W. Orlowski Independent Public Clinical Hospital, Centre of Postgraduate Medical Education, Warsaw, Poland.
Wojciech WalasDepartment for Anesthesiology and Intensive Care Unit for Children and Neonates, Clinical University Hospital, Opole, Poland.
Ewa KamińskaDepartment of Pharmacology, Institute of Mother and Child, Warsaw, Poland.
Małgorzata Malec MilewskaDepartment for Anesthesiology and Intensive Care, Prof. W. Orlowski Independent Public Clinical Hospital, Centre of Postgraduate Medical Education, Warsaw, Poland.
Agnieszka SękowskaDepartment for Anesthesiology and Intensive Care, Prof. W. Orlowski Independent Public Clinical Hospital, Centre of Postgraduate Medical Education, Warsaw, Poland.
Ewa HelwichDepartment for Neonatology and Neonatal Intensive Care, Institute of Mother and Child, Warsaw, Poland.
Grochowski Hospital · PLMother and Child Foundation · GBPostgraduate School of Molecular Medicine · PLUniversity of Opole · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The issues concerning the transfer of drugs into mothers' milk and their influence on breastfed babies have not been fully studied. Assessment of the situation should include such aspects as drug transfer into fetal blood and into mother's milk, the real risk of inhibiting lactogenesis 2 in women after birth, as well as the psychological consequences for the mother of suspending breastfeeding. The risk of feeding a newborn with formula based on cow's milk is another fateful issue. The following paper presents the pharmacokinetic characteristics of drugs which determine their transfer level through the placenta and into mother's milk during the perinatal period and lactation.

Indexed as

AnesthesiaAnesthesia, ObstetricalAnestheticsBreast FeedingDrug-Related Side Effects and Adverse ReactionsFemaleHumansInfantInfant, NewbornInfant Nutritional Physiological PhenomenaLactationMilk, HumanPregnancyTime FactorsAnestheticsanesthesiabreastfeedingcesarean sectiondeliverydrugs

Identifiers

PMID31913138
PMCPMC11864499
OpenAlexW3002059718

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.