Trial reportAnnals of oncology : official journal of the European Society for Medical Oncology2020
Differential effects of an electronic symptom monitoring intervention based on the age of patients with advanced cancer.
Trial report in Annals of oncology : official journal of the European Society for Medical Oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 41 citations in OpenAlex.
- Physiological and psychological symptom management based on electronic patient-reported outcomes: the TD-WELLBEING randomized clinical trial.British journal of cancer · 2025Trial
- Trial
- Quality of life after patient-initiated vs physician-initiated response to symptom monitoring: the SYMPRO-Lung trial.Journal of the National Cancer Institute · 2023Trial
- Sociodemographic Characteristics Predicting Digital Health Intervention Use After Acute Myocardial Infarction.Journal of cardiovascular translational research · 2021Trial
- Using Electronic Patient-Reported Outcome Measures for Patients With Metastatic Renal Cell Carcinoma: A Narrative Review.Clinical journal of oncology nursing · 2025Review
- Article
- Big Data for Geriatric Oncology Research.North Carolina medical journal · 2024Article
- Care Delivery Interventions for Individuals with Cancer: A Literature Review and Focus on Gastrointestinal Malignancies.Healthcare (Basel, Switzerland) · 2023Review
- Symptom burden in patients with idiopathic multicentric Castleman disease and its impact on daily life: an international patient and caregiver survey.EClinicalMedicine · 2023Article
- Enhanced supportive care for advanced cancer patients: study protocol for a randomized controlled trial.BMC nursing · 2022Article
- A mixed methods pilot and feasibility open trial of internet-delivered cognitive behaviour therapy (Internet interventions · 2021Article
- Additional Value of Patient-Reported Symptom Monitoring in Cancer Care: A Systematic Review of the Literature.Cancers · 2021Review
- Understanding Treatment Tolerability in Older Adults With Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2021Review
- Convergence of Geriatrics and Palliative Care to Deliver Personalized Supportive Care for Older Adults With Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2021Review
- Caregiver-Oncologist Prognostic Concordance, Caregiver Mastery, and Caregiver Psychological Health and Quality of Life.The oncologist · 2021Article
- Comparing Clinician-Assessed and Patient-Reported Performance Status for Predicting Morbidity and Mortality in Patients With Advanced Cancer Receiving Chemotherapy.JCO oncology practice · 2021Article
- AMTRA: a multicentered experience of a web-based monitoring and tailored toxicity management system for cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
- A narrative review of current evidence supporting the implementation of electronic patient-reported outcome measures in the management of chronic diseases.Therapeutic advances in chronic disease · 2021Article
- Capacity to Provide Geriatric Specialty Care for Older Adults in Community Oncology Practices.The oncologist · 2020Article
- COVID-19 Emergency and the Need to Speed Up the Adoption of Electronic Patient-Reported Outcomes in Cancer Clinical Practice.JCO oncology practice · 2020Article
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundSymptom monitoring interventions enhance patient outcomes, including quality of life (QoL), health care utilization, and survival, but it remains unclear whether older and younger patients with cancer derive similar benefits. We explored whether age moderates the improved outcomes seen with an outpatient electronic symptom monitoring intervention. PATIENTS AND
methodsWe carried out a secondary analysis of data from a randomized trial of 766 patients receiving chemotherapy for metastatic solid tumors. Patients received an electronic symptom monitoring intervention integrated with oncology care or usual oncology care alone. The intervention consisted of patients reporting their symptoms, which were provided to their physicians at clinic visits, and nurses receiving alerts for severe/worsening symptoms. We used regression models to determine whether age (older or younger than 70 years) moderated the effects of the intervention on QoL (EuroQol EQ-5D), emergency room (ER) visits, hospitalizations, and survival outcomes.
resultsEnrollment rates for younger (589/777 = 75.8%) and older (177/230 = 77.0%) patients did not differ. Older patients (median age = 75 years, range 70-91 years) were more likely to have an education level of high school or less (26.6% versus 20.9%, P = 0.029) and to be computer inexperienced (50.3% versus 23.4%, P < 0.001) compared with younger patients (median age = 58 years, range 26-69 years). Younger patients receiving the symptom monitoring intervention experienced lower risk of ER visits [hazard ratio (HR) = 0.74, P = 0.011] and improved survival (HR = 0.76, P = 0.011) compared with younger patients receiving usual care. However, older patients did not experience significantly lower risk of ER visits (HR = 0.90, P = 0.613) or improved survival (HR = 1.06, P = 0.753) with the intervention. We found no moderation effects based on age for QoL and risk of hospitalizations.
conclusionsAmong patients with advanced cancer, age moderated the effects of an electronic symptom monitoring intervention on the risk of ER visits and survival, but not QoL. Symptom monitoring interventions may need to be tailored to the unique needs of older adults with cancer.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.