Evidence map›Paper›PMID 31912618›Full record

ArticleJournal of diabetes investigation2020

Intra-individual association between C-reactive protein and insulin administration in postoperative lumbar spinal canal stenosis patients: A retrospective cohort study.

Ken Kurisu, Yuya Tsurutani, Kosuke Inoue, Yoshitomo Hoshino, Fumiko Saiki, Kazuhiro Yoshiuchi

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in Journal of diabetes investigation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Ken KurisuDepartment of Endocrinology and Diabetes Center, Yokohama Rosai Hospital, Yokohama, Japan.ORCID https://orcid.org/0000-0002-1831-8987
Yuya TsurutaniDepartment of Endocrinology and Diabetes Center, Yokohama Rosai Hospital, Yokohama, Japan.ORCID https://orcid.org/0000-0001-5831-3286
Kosuke InoueDepartment of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, California, USA.
Yoshitomo HoshinoDepartment of Endocrinology and Diabetes Center, Yokohama Rosai Hospital, Yokohama, Japan.
Fumiko SaikiDepartment of Orthopedic Surgery, Yokohama Rosai Hospital, Yokohama, Japan.
Kazuhiro YoshiuchiDepartment of Stress Sciences and Psychosomatic Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Yokohama Rosai Hospital · JPThe University of Tokyo · JPUCLA Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The association of intra-individual variability in insulin requirements with C-reactive protein levels among acute phase patients remains unclear. This retrospective cohort study aimed to evaluate this association. Patients with type 2 diabetes undergoing surgery for lumbar spinal canal stenosis were included in the study. We analyzed 286 records of 49 patients using the linear mixed effects model. The model showed C-reactive protein levels to be significantly associated with insulin requirements, with an effect size of 0.60 U/day for an elevation of 1 mg/dL. The effect size was increased in patients with higher hemoglobin A1c levels. Our findings imply that C-reactive protein levels could be a useful clinical biomarker when blood glucose levels are controlled in acute phase patients.

Indexed as

AgedBiomarkersC-Reactive ProteinDiabetes Mellitus, Type 2FemaleHumansHypoglycemic AgentsInsulinLinear ModelsLongitudinal StudiesLumbar VertebraeMalePostoperative PeriodRetrospective StudiesSpinal StenosisBiomarkersC-Reactive ProteinHypoglycemic AgentsInsulinC-reactive proteinInsulinLinear mixed effects model

Identifiers

PMID31912618
PMCPMC7378432
OpenAlexW2999280575

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.