Evidence map›Paper›PMID 31912356›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2020

Social inequalities in health-related quality of life among people aging with HIV/AIDS: the role of comorbidities and disease severity.

Jochen Drewes, Jennifer Ebert, Phil C Langer, Dieter Kleiber, Burkhard Gusy

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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Jochen DrewesPublic Health: Prevention and Psychosocial Health Research, Freie Universität Berlin, Habelschwerdter Allee 45, 14195, Berlin, Germany. jochen.drewes@fu-berlin.de.ORCID http://orcid.org/0000-0002-9707-2056
Jennifer EbertPublic Health: Prevention and Psychosocial Health Research, Freie Universität Berlin, Habelschwerdter Allee 45, 14195, Berlin, Germany.
Phil C LangerInternational Psychoanalytic University, Stromstr. 3b, 10555, Berlin, Germany.
Dieter KleiberPublic Health: Prevention and Psychosocial Health Research, Freie Universität Berlin, Habelschwerdter Allee 45, 14195, Berlin, Germany.
Burkhard GusyPublic Health: Prevention and Psychosocial Health Research, Freie Universität Berlin, Habelschwerdter Allee 45, 14195, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWhile socioeconomic inequalities in health-related quality of life are well documented in the scientific literature, research has neglected to look into the reasons for these inequalities. The purpose of this study is to determine in what way social inequalities in health-related quality of life among patients with the same chronic disease could be explained by variations in disease severity.

methodsWe used the data of 748 people aging with HIV in Germany who took part in the nationwide study 50plushiv and provided self-report data on socioeconomic status, health-related quality of life (SF-12) and various markers of disease severity (comorbidity, falls, late presentation and AIDS diagnosis). Regression analyses were applied to determine the impact of SES on HRQOL after adjusting for disease severity variables.

resultsThe mental and physical subscales of the SF-12, comorbidity burden and falls were significantly related to SES. SES explained 7% of the variance in PCS scores and 3% of the variance in MCS scores after adjusting for age and time since diagnosis. Markers of disease severity explained 33% of the variance in PCS scores and 14% of the variance in MCS scores. After adjusting for disease severity SES was still significantly related to PCS and MCS scores.

conclusionsThe diverse sample of people aging with HIV showed social inequalities regarding HRQOL and most of the disease severity markers. SES was significantly related to mental and physical HRQOL after adjusting for disease severity. Possible explanations for this phenomenon are discussed.

Indexed as

Acquired Immunodeficiency SyndromeChronic DiseaseComorbidityFemaleHIVHumansMaleMiddle AgedQuality of LifeSocioeconomic FactorsDisease severityHealth inequalitiesHealth-related quality of lifeHIVSocioeconomic status

Identifiers

PMID31912356
PMCPMC8255252

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.