ArticleProbiotics and antimicrobial proteins2020
Effect of Application of Probiotic Pollen Suspension on Immune Response and Gut Microbiota of Honey Bees (Apis mellifera).
Article in Probiotics and antimicrobial proteins, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 49 citations in OpenAlex.
- The honeybee gut microbiome: a novel multidimensional model of antimicrobial resistance transmission and immune homeostasis from environmental interactions to health regulation.FEMS microbiology reviews · 2026Review
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- Dietary modulation of gut microbiota and functional enzymes in savannah honey bees (Apis mellifera scutellata Lepeletier).Applied microbiology and biotechnology · 2025Article
- Molecular Assessment of Genes Linked to Honeybee Health Fed with Different Diets in Nuclear Colonies.Insects · 2025Article
- Effects of synergistic fermentation of tea bee pollen with bacteria and enzymes on growth and intestinal health ofCurrent research in microbial sciences · 2025Article
- Article
- Dual roles of nanocrystalline cellulose extracted from jute (Nanoscale advances · 2023Article
- Probiotics and in-hive fermentation as a source of beneficial microbes to support the gut microbial health of honey bees.Journal of insect science (Online) · 2023Review
- Biocontrol potential of Apilactobacillus kunkeei EIR/BG-1 against infectious diseases in honey bees (Apis mellifera L.).Veterinary research communications · 2023Article
- Isolation and characterization ofSaudi journal of biological sciences · 2023Article
- Characterization and Protective Properties of Lactic Acid Bacteria Intended to Be Used in Probiotic Preparation for Honeybees (Animals : an open access journal from MDPI · 2023Article
- Trans-Anethole Alleviates DSS-Induced Ulcerative Colitis by Remodeling the Intestinal Flora to Regulate Immunity and Bile Acid Metabolism.Mediators of inflammation · 2023Article
- The Intestinal Immune Defense System in Insects.International journal of molecular sciences · 2022Review
- The Gut Microbiota at Different Developmental Stages ofMicroorganisms · 2022Article
- Detection Bioactive Metabolites of Fructobacillus fructosus Strain HI-1 Isolated from Honey Bee's Digestive Tract Against Paenibacillus larvae.Probiotics and antimicrobial proteins · 2022Article
- Biological Functions of Exopolysaccharides from Lactic Acid Bacteria and Their Potential Benefits for Humans and Farmed Animals.Foods (Basel, Switzerland) · 2022Review
- Bugs in Bugs: The Role of Probiotics and Prebiotics in Maintenance of Health in Mass-Reared Insects.Insects · 2022Review
- Probiotic Potential and Effects on Gut Microbiota Composition and Immunity of Indigenous Gut Lactobacilli in Apis cerana.Probiotics and antimicrobial proteins · 2022Article
- Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although the use of probiotic bacteria in invertebrates is still rare, scientists have begun to look into their usage in honey bees. The probiotic preparation, based on the autochthonous strain Lactobacillus brevis B50 Biocenol™ (CCM 8618), which was isolated from the digestive tracts of healthy bees, was applied to the bee colonies in the form of a pollen suspension. Its influence on the immune response was determined by monitoring the expression of genes encoding immunologically important molecules in the honey bee intestines. Changes in the intestinal microbiota composition were also studied. The results showed that the probiotic Lact. brevis B50, on a pollen carrier, significantly increased the expression of genes encoding antimicrobial peptides (abaecin, defensin-1) as well as pattern recognition receptors (toll-like receptor, peptidoglycan recognition proteins). Gene expression for the other tested molecules included in Toll and Imd signaling pathways (dorsal, cactus, kenny, relish) significantly changed during the experiment. The positive effect on intestinal microbiota was manifested mainly by a significant increase in the ratio of lactic acid bacteria to enterobacteria. These findings confirm the potential of the tested probiotic preparation to enhance immunity in bee colonies and thus increase their resistance to infectious diseases and stress conditions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.