SynthesisNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2020
Theory of mind in Alzheimer's disease and amnestic mild cognitive impairment: a meta-analysis.
Synthesis in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Social cognition in mild cognitive impairment and dementia: A systematic review and meta-analysis.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Pooled it
- Empathy and Theory of Mind in Multiple Sclerosis: A Meta-Analysis.Frontiers in psychiatry · 2021Pooled it
- Moral decision-making in real and sacrificial contexts: a pilot study on social cognition in mild cognitive impairment.BMC psychology · 2026Article
- Mini-SEA: Validity and Normative Data for the French-Quebec Population Aged 50 Years and Above.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025Article
- Comparing the benefits of Cognitive Stimulation Therapy with an adapted collaborative version on traditional outcomes, loneliness, and socioemotional skills: a pilot study.Frontiers in psychology · 2025Article
- Reading the mind in the eyes in patients with idiopathic REM sleep behavior disorder.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Reliability and minimal detectable change of the Yoni task for the theory of mind assessment.Frontiers in psychology · 2024Article
- Theory of Mind and Executive Functions in Individuals with Mild Cognitive Impairment or Healthy Aging.Brain sciences · 2023Article
- Constructing a prognostic risk model for Alzheimer's disease based on ferroptosis.Frontiers in aging neuroscience · 2023Article
- Pilot Randomized, Double-Blind, Placebo-Controlled Crossover Trial Evaluating the Feasibility of an Intranasal Oxytocin in Improving Social Cognition in Individuals Living with Alzheimer's Disease.Journal of Alzheimer's disease reports · 2023Article
- Affective Theory of Mind as a residual ability to preserve mentalizing in amnestic Mild Cognitive Impairment: A 12-months longitudinal study.Frontiers in neurology · 2022Article
- Predicting financial deficits from a standard neuropsychological assessment: preliminary evidence in mild cognitive impairment.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Article
- Socially desirable responding in geriatric outpatients with and without mild cognitive impairment and its association with the assessment of self-reported mental health.BMC geriatrics · 2021Article
- The role of microglia in the development of neurodegeneration.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020Review
- Empathy and theory of mind in multiple sclerosis: A protocol for systematic review and meta-analysis.Medicine · 2020Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe assessment of theory of mind (ToM) performance in Alzheimer's disease (AD) and amnestic mild cognitive impairment (aMCI) remains inconclusive. We conducted a meta-analysis to investigate ToM performance in patients with aMCI and AD.
methodsA systematic literature search was performed for eligible studies published up to July 2019 in three international databases (PubMed, Embase, and Web of Science). Due to heterogeneity between studies, a random-effects model was used. Individual ToM tasks were meta-analyzed separately and possible sources of heterogeneity were examined.
resultsIn total, 36 studies involving 701 individuals with AD and 197 with aMCI were identified. Compared with healthy controls, ToM was impaired in both AD (d = 1.45) and aMCI patients (d = 0.65). In AD patients, ToM was particularly impaired in advanced tasks such as Faux Pas Recognition (d = 1.26). In patients with aMCI, ToM deficits were relatively modest, with the exception of the reading the mind in the eyes task (d = 1.22). ToM was significantly more impaired in AD than that in aMCI (d = 0.88).
conclusionsThis is the first meta-analysis examining ToM performance in AD and aMCI simultaneously. The results showed that ToM deficits were more severe in AD than that in aMCI in most individual ToM tasks. Longitudinal studies are warranted to determine whether ToM abilities in aMCI patients can be used for prognostic purposes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.