Evidence map›Paper›PMID 31912277›Full record

ArticleMolecular and cellular biochemistry2020

Collagen receptor- and metalloproteinase-dependent hypertensive stress response in mesangial and glomerular endothelial cells.

Suravi Majumder, Matthew Amin, Sathnur Pushpakumar, Utpal Sen

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular and cellular biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Diabetic Nephropathy and Gaseous Modulators.Antioxidants (Basel, Switzerland) · 2023
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Suravi MajumderDepartment of Physiology, School of Medicine, University of Louisville, Louisville, KY, 40202, USA.
Matthew AminDepartment of Physiology, School of Medicine, University of Louisville, Louisville, KY, 40202, USA.
Sathnur PushpakumarDepartment of Physiology, School of Medicine, University of Louisville, Louisville, KY, 40202, USA.
Utpal SenDepartment of Physiology, School of Medicine, University of Louisville, Louisville, KY, 40202, USA. u0sen001@louisville.edu.ORCID http://orcid.org/0000-0002-0600-3443
University of Louisville · US

Funding

Hydrogen sulfide mechanism of renal hypertensionR01DK104653 · NIDDK · UNIVERSITY OF LOUISVILLE · PI SEN, UTPAL, TYAGI, SURESH C. · 2015 to 2018
$2.5M
miRNA Mechanism of Acute Kidney Injury in AgingR01DK116591 · NIDDK · UNIVERSITY OF LOUISVILLE · PI SEN, UTPAL, TYAGI, SURESH C. · 2018 to 2022
$2.2M
NIDDK NIH HHS DK104653NIDDK NIH HHS DK116591NIDDK NIH HHS R01 DK104653NIDDK NIH HHS R01 DK116591
6 · The paper itself

Abstract

Progressive alteration of the extracellular matrix (ECM) is the characteristic of hypertensive nephropathy (HN). Both mesangial and endothelial cells have the ability to synthesize and degrade ECM components, including collagens through the activation of matrix metalloproteinases (MMPs) in stress conditions, such as in hypertension. On the other hand, hydrogen sulfide (H

Indexed as

Stress, PhysiologicalAnimalsEndothelial CellsGlomerular MesangiumHypertension, RenalMatrix Metalloproteinase 13Matrix Metalloproteinase 14MiceReceptors, CollagenMatrix Metalloproteinase 13Matrix Metalloproteinase 14Mmp13 protein, mouseMmp14 protein, mouseReceptors, CollagenCollagenEndo180H2SMMPPAI-1TIMPtPA

Identifiers

PMID31912277
PMCPMC10809865
OpenAlexW2999532136

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.