Evidence map›Paper›PMID 31912200›Full record

ArticleApplied microbiology and biotechnology2020

Oral delivery of Bacillus subtilis spores expressing Clonorchis sinensis paramyosin protects grass carp from cercaria infection.

Hengchang Sun, Mei Shang, Zeli Tang, Hongye Jiang, Huimin Dong, Xinyi Zhou, Zhipeng Lin, Cunbin Shi, Pengli Ren, Lu Zhao and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in Applied microbiology and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
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  9. Frontiers in immunology · 2022
    Article
  10. Article
  11. Review
  12. Article
  13. Molecular Mechanisms ofFrontiers in cell and developmental biology · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Hengchang SunDepartment of Laboratory Medicine, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Mei ShangDepartment of Laboratory Medicine, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Zeli TangDepartment of Cell Biology and Genetics, School of Pre-clinical Medicine, Guangxi Medical University, Nanning, 530021, China.
Hongye JiangDepartment of parasitology, Zhongshan School of medicine, Sun Yat-sen University, Guangzhou, China.
Huimin DongDepartment of Laboratory Medicine, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Xinyi ZhouDepartment of parasitology, Zhongshan School of medicine, Sun Yat-sen University, Guangzhou, China.
Zhipeng LinDepartment of parasitology, Zhongshan School of medicine, Sun Yat-sen University, Guangzhou, China.
Cunbin ShiKey Laboratory of Fishery Drug Development, Ministry of Agriculture, Pearl River, Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou, Guangdong, China.
Pengli RenDepartment of parasitology, Zhongshan School of medicine, Sun Yat-sen University, Guangzhou, China.
Lu ZhaoDepartment of parasitology, Zhongshan School of medicine, Sun Yat-sen University, Guangzhou, China.
Mengchen ShiDepartment of parasitology, Zhongshan School of medicine, Sun Yat-sen University, Guangzhou, China.
Lina ZhouDepartment of parasitology, Zhongshan School of medicine, Sun Yat-sen University, Guangzhou, China.
Houjun PanKey Laboratory of Fishery Drug Development, Ministry of Agriculture, Pearl River, Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou, Guangdong, China.
Ouqin ChangKey Laboratory of Fishery Drug Development, Ministry of Agriculture, Pearl River, Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou, Guangdong, China.
Xuerong LiDepartment of parasitology, Zhongshan School of medicine, Sun Yat-sen University, Guangzhou, China.
Yan HuangDepartment of parasitology, Zhongshan School of medicine, Sun Yat-sen University, Guangzhou, China. huang66@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0002-6751-4669
Xinbing YuDepartment of parasitology, Zhongshan School of medicine, Sun Yat-sen University, Guangzhou, China. yuxb@mail.sysu.edu.cn.
Sun Yat-sen University · CNChinese Academy of Fishery Sciences · CNGuangxi Medical University · CN

Funding

Guangdong marine economy promotion projects fund GDOE[2019]A29the national key research and development program of China 2017YFD0501300the science and technology planning project of Guangdong province No.2014B020203001
6 · The paper itself

Abstract

Clonorchis sinensis (C. sinensis), an important fishborne zoonotic parasite threatening public health, is of major socioeconomic importance in epidemic areas. Effective strategies are still urgently expected to prevent against C. sinensis infection. In the present study, paramyosin of C. sinensis (CsPmy) was stably and abundantly expressed on the surface of Bacillus subtilis spores. The recombinant spores (B.s-CotC-CsPmy) were incorporated in the basal pellets diet in three different dosages (1 × 10

Indexed as

Bacillus subtilisSpores, BacterialAdministration, OralAnimal FeedAnimalsAntibodies, HelminthCarpsCercariaClonorchiasisClonorchis sinensisFish DiseasesImmunoglobulin MIntestinesTropomyosinVaccinesAntibodies, HelminthImmunoglobulin MTropomyosinVaccinesBacillus subtilis sporeClonorchis sinensisGrass carpIntestinal microbiotaOral vaccineParamyosin

Identifiers

PMID31912200
PMCPMC7223688
OpenAlexW2999823857

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.