ArticleThe American journal of clinical nutrition2020
Dietary Patterns and Progression of Knee Osteoarthritis: Data from the Osteoarthritis Initiative.
Article in The American journal of clinical nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 4 of them syntheses that pooled it.
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Who cites it
32 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Evidence-Based Dietary Practices to Improve Osteoarthritis Symptoms: An Umbrella Review.Nutrients · 2023Pooled it
- Effect of omega-3 polyunsaturated fatty acids supplementation for patients with osteoarthritis: a meta-analysis.Journal of orthopaedic surgery and research · 2023Pooled it
- The effects of dietary patterns and food groups on symptomatic osteoarthritis: A systematic review.Nutrition & dietetics : the journal of the Dietitians Association of Australia · 2023Pooled it
- Defining and predicting radiographic knee osteoarthritis progression: a systematic review of findings from the osteoarthritis initiative.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022Pooled it
- Health-Related Behaviors Associated With Knee Pain Increase: A Longitudinal Community-Based Cohort Study That Examines Osteoarthritis.ACR open rheumatology · 2026Article
- Barriers and facilitators for consuming a plant-based diet in patients with knee osteoarthritis: a qualitative study.Frontiers in nutrition · 2026Article
- Production of a risk mitigation matrix and four-grade threshold scale using Cox Regression to predict osteoarthritis development.Open life sciences · 2026Article
- Association between Diet Quality and Knee Osteoarthritis: Insights from the Korea National Health and Nutrition Examination Survey 2013.Journal of bone metabolism · 2025Article
- Plasma Glycated and Oxidized Amino Acid-Based Screening Test for Clinical Early-Stage Osteoarthritis.Antioxidants (Basel, Switzerland) · 2025Article
- Ultra-processed food consumption is associated with knee osteoarthritis: Data from the Osteoarthritis Initiative.Osteoarthritis and cartilage · 2025Article
- Diet in Knee Osteoarthritis-Myths and Facts.Nutrients · 2025Review
- Central obesity and radiographic severity are associated with symptomatic hand osteoarthritis: a population-based cross-sectional study.Rheumatology international · 2025Article
- Non-Pharmacological Pain Management for Osteoarthritis: Review Update.Current rheumatology reports · 2025Review
- Association of dietary acid load with inflammatory markers, oxidative stress, and clinical features in patients with knee osteoarthritis.Scientific reports · 2025Article
- Global, regional, and national burden of osteoarthritis among middle-aged and older adults: estimates from the global burden of disease study 2021 and projections to 2050.Frontiers in medicine · 2025Review
- Global, regional, and national burden of knee osteoarthritis attributable to high BMI: a systematic analysis from 1990 to 2021 and projections to 2050.Frontiers in public health · 2025Article
- Rising direct medical costs of osteoarthritis in Germany from 2002 to 2020: trends, demographic drivers, and public health considerations.Frontiers in public health · 2025Article
- Association between Dietary total antioxidant capacity and knee osteoarthritis: a case-control study in the Iranian Population.BMC musculoskeletal disorders · 2024Article
- Wharton's jelly and osteoarthritis of the knee.British medical bulletin · 2024Review
- [Dietary inflammatory index related to knee osteoarthritis symptomatology].Revista medica del Instituto Mexicano del Seguro Social · 2024Observational
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Authors and funding
6 authors.
Funding
Abstract
backgroundWhile some individual foods and nutrients have been associated with knee osteoarthritis (KOA) progression, the association between dietary patterns and KOA progression has received little research attention.
objectiveThe objective of this study was to determine whether dietary patterns, derived by principal components analysis (PCA), are associated with KOA progression.
methodsIn the Osteoarthritis Initiative (OAI), a prospective cohort with clinical centers in Maryland, Ohio, Pennsylvania, and Rhode Island, 2757 participants with existing KOA (mean age 62 y) and diet assessed at baseline were followed for ≤72 mo. Using PCA, Western and prudent dietary patterns were derived. Radiographic KOA progression was assessed using 2 separate measures, 1 full Kellgren-Lawrence (KL) grade increase and loss in joint space width (JSW). Symptomatic KOA progression was defined as an increase in or remaining in 1 of the 2 highest classification categories of the Western Ontario and McMaster Universities Arthritis Index (WOMAC).
resultsAdherence to Western and prudent dietary patterns was significantly associated with radiographic and symptomatic progression of KOA. With increasing Western pattern score, there was increased KL-worsening risk (compared with quartile 1, HR for quartile 4: 1.30; 95% CI: 1.05, 1.61; P-trend < 0.01) and increased odds of progression to higher WOMAC score (compared with quartile 1, OR for quartile 4: 1.39; 95% CI: 1.18, 1.63; P-trend < 0.01) but no significant change in JSW loss. With increasing prudent pattern score there was decreased KL-worsening risk (compared with quartile 1, HR for quartile 4: 0.79; 95% CI: 0.64, 0.98; P-trend = 0.02), decreased JSW loss (quartile 1: 0.46 mm; quartile 4: 0.38 mm; P-trend < 0.01), and decreased odds of higher WOMAC progression (compared with quartile 1, OR for quartile 4 0.73; 95% CI: 0.62, 0.86; P-trend < 0.01) in multivariable adjusted models.
conclusionsAdherence to a Western dietary pattern was associated with increased radiographic and symptomatic KOA progression, while following a prudent pattern was associated with reduced progression. In general, for people already diagnosed with KOA, eating a diet rich in fruits, vegetables, fish, whole grains, and legumes may be related to decreased radiographic and symptomatic disease progression.
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