Evidence map›Paper›PMID 31911854›Full record

ArticleAmerican journal of cancer research2019

YY1 promotes colorectal cancer proliferation through the

Zejun Fang, Hua Yang, Dan Chen, Xiaoying Shi, Qinqiu Wang, Chaoju Gong, Xi Xu, Hong Liu, Min Lin, Junxiao Lin and 2 more

Open access · greenAbstract read
In one paragraph

Article in American journal of cancer research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. The YYR (YY1- RKIP) Regulatory Axis in the pathogenesis of Cancer and Immune Evasion.Journal of experimental & clinical cancer research : CR · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Loss of DNA Polymerase β Delays Atherosclerosis inInternational journal of molecular sciences · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
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  16. Article
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  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Zejun FangDepartment of Gastroenterology, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, China.
Hua YangDepartment of Gastroenterology, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, China.
Dan ChenDepartment of Gastroenterology, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, China.
Xiaoying ShiDepartment of Gastroenterology, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, China.
Qinqiu WangDepartment of Gastroenterology, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, China.
Chaoju GongCentral Laboratory, The Municipal Affiliated Hospital of Xuzhou Medical University Xuzhou, China.
Xi XuDepartment of Pathology, The Second Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, China.
Hong LiuZhejiang Normal University, Jinhua People's Hospital Joint Center for Biomedical Research Jinhua, China.
Min LinCentral Laboratory, Sanmenwan Branch, The First Affiliated Hospital, College of Medicine, Zhejiang University Sanmen, China.
Junxiao LinCentral Laboratory, Sanmenwan Branch, The First Affiliated Hospital, College of Medicine, Zhejiang University Sanmen, China.
Chengfu XuDepartment of Gastroenterology, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, China.
Jimin ShaoDepartment of Pathology and Pathophysiology, College of Medicine, Zhejiang University Hangzhou, China.
Zhejiang University · CNSecond Affiliated Hospital of Zhejiang University · CNZhejiang Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We previously reported that E2F1 expression is up-regulated and positively correlated with the malignant phenotypes of colorectal cancer (CRC). However, the underlying mechanisms leading to the aberrant up-regulation of E2F1 in CRC have not been clarified. In this study, we observed that

Indexed as

colorectal cancerE2F1miR-526b-3pproliferationYing Yang 1

Identifiers

PMID31911854
PMCPMC6943347
OpenAlexW3002722819

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.