ArticleBiotechnology for biofuels2020
Enhanced lipid production by
Article in Biotechnology for biofuels, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 128 citations in OpenAlex.
- Process Engineering Strategies for Microbial Lipid Production: From Strain Evolution to Industrial-Scale Bioprocessing.International journal of molecular sciences · 2026Review
- Regulatory effects of carbon and nitrogen nutrition on lipid accumulation by Yarrowia lipolytica cultivated with high-concentration volatile fatty acids.Bioprocess and biosystems engineering · 2026Article
- Recent advances in microbial production of odd-chain fatty acids.World journal of microbiology & biotechnology · 2026Review
- Transcriptomics-based analysis of acetate and propionate transport and metabolism in Yarrowia lipolytica.Biotechnology for biofuels and bioproducts · 2025Article
- Advances in Lycopene Production: From Natural Sources to Microbial Synthesis UsingMolecules (Basel, Switzerland) · 2025Article
- Impact of glucose and propionic acid on even and odd chain fatty acid profiles of oleaginous yeasts.BMC microbiology · 2025Article
- Substrate-dependent lipid and β-carotene production in engineered Yarrowia lipolytica: a comparative study.AMB Express · 2025Article
- Turning residues into valuable compounds: organic waste conversion into odd-chain fatty acids via the carboxylate platform by recombinant oleaginous yeast.Microbial cell factories · 2025Article
- High-throughput screening of non-conventional yeasts for conversion of organic waste to microbial oils via carboxylate platform.Scientific reports · 2024Article
- Simultaneous production of biofuel from agricultural wastes and bioremediation of the waste substrates: A review.Current research in microbial sciences · 2024Review
- Production of short-chain fatty acids (SCFAs) as chemicals or substrates for microbes to obtain biochemicals.Biotechnology for biofuels and bioproducts · 2023Review
- Yarrowia lipolytica produces lipid-rich biomass in medium mimicking lignocellulosic biomass hydrolysate.Applied microbiology and biotechnology · 2023Article
- Microbial Lipid Based Biorefinery Concepts: A Review of Status and Prospects.Foods (Basel, Switzerland) · 2023Review
- The microbial food revolution.Nature communications · 2023Review
- Phosphate limitation as crucial factor to enhance yeast lipid production from short-chain fatty acids.Microbial biotechnology · 2023Article
- Biotechnological production of omega-3 fatty acids: current status and future perspectives.Frontiers in microbiology · 2023Review
- Tailoring and optimizing fatty acid production by oleaginous yeasts through the systematic exploration of their physiological fitness.Microbial cell factories · 2022Article
- Survey of nonconventional yeasts for lipid and hydrocarbon biotechnology.Journal of industrial microbiology & biotechnology · 2022Article
- Exploring Yeast Diversity to Produce Lipid-Based Biofuels from Agro-Forestry and Industrial Organic Residues.Journal of fungi (Basel, Switzerland) · 2022Review
- Microbial Utilization of Next-Generation Feedstocks for the Biomanufacturing of Value-Added Chemicals and Food Ingredients.Frontiers in bioengineering and biotechnology · 2022Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVolatile fatty acids (VFAs) can be effective and promising alternate carbon sources for microbial lipid production by a few oleaginous yeasts. However, the severe inhibitory effect of high-content (> 10 g/L) VFAs on these yeasts has impeded the production of high lipid yields and their large-scale application. Slightly acidic conditions have been commonly adopted because they have been considered favorable to oleaginous yeast cultivation. However, the acidic pH environment further aggravates this inhibition because VFAs appear largely in an undissociated form under this condition. Alkaline conditions likely alleviate the severe inhibition of high-content VFAs by significantly increasing the dissociation degree of VFAs. This hypothesis should be verified through a systematic research.
resultsThe combined effects of high acetic acid concentrations and alkaline conditions on VFA utilization, cell growth, and lipid accumulation of
conclusionsThis study assumed and verified that alkaline conditions (optimal pH 8) could effectively alleviate the lethal effect of high-content VFA on
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.