Evidence map›Paper›PMID 31911647›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2020

Outcomes of neonates born at <26 weeks gestational age who receive extensive cardiopulmonary resuscitation compared with airway and breathing support.

Vivek Shukla, Omar Elkhateeb, Prakesh S Shah, Junmin Yang, Kyong-Soon Lee, Canadian Neonatal Network Investigators

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Vivek ShuklaDivision of Neonatology, Department of Pediatrics, The Hospital for Sick Children, Room 38102, 555 University Avenue, Toronto, ON, M5G 1X8, Canada.ORCID http://orcid.org/0000-0003-1580-1049
Omar ElkhateebDivision of Neonatology, Department of Pediatrics, The Hospital for Sick Children, Room 38102, 555 University Avenue, Toronto, ON, M5G 1X8, Canada.ORCID http://orcid.org/0000-0002-3472-9145
Prakesh S ShahDepartment of Pediatrics, Mount Sinai Hospital, Toronto, ON, Canada.
Junmin YangMaternal-Infant Care Research Centre, Mount Sinai Hospital, Toronto, ON, Canada.
Kyong-Soon LeeDivision of Neonatology, Department of Pediatrics, The Hospital for Sick Children, Room 38102, 555 University Avenue, Toronto, ON, M5G 1X8, Canada. kyong-soon.lee@sickkids.ca.
Canadian Neonatal Network Investigators
Mount Sinai Hospital · CAHospital for Sick Children · CAUniversity of Toronto · CA

Funding

CIHR APR-126340CIHR CTP 87518
6 · The paper itself

Abstract

objectiveTo evaluate outcomes of preterm infants <26 weeks gestational age (GA) following postdelivery extensive cardiopulmonary resuscitation (ECPR) compared with airway and breathing support (ABS). STUDY

designRetrospective review of Canadian Neonatal Network data during January 2010 to December 2016. The primary outcome was death or severe morbidity (intraventricular hemorrhage ≥grade 3 or periventricular leucomalacia, retinopathy of prematurity ≥stage 3, bronchopulmonary dysplasia, or necrotizing enterocolitis).

resultAmong 3633 infants analyzed, 433 (11.9%) received ECPR. In multivariable analysis, death or severe morbidity was higher in the ECPR versus ABS group [adjusted odds ratio 2.26 (95% confidence interval 1.49, 3.43)]. The majority of the difference was due to increased mortality, which occurred mostly during the first week of life.

conclusionThese data from a recent cohort of infants near the limits of viability may be useful for prognostication for health care providers and counseling of parents.

Indexed as

Cardiopulmonary ResuscitationInfant, Extremely PrematurePerinatal DeathPositive-Pressure RespirationBronchopulmonary DysplasiaCanadaCerebral HemorrhageEnterocolitis, NecrotizingFemaleHumansInfant, NewbornIntubation, IntratrachealKaplan-Meier EstimateMaleMultivariate AnalysisPrognosis

Identifiers

PMID31911647
OpenAlexW3000479660

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.