Evidence map›Paper›PMID 31911634›Full record

ArticleLaboratory investigation; a journal of technical methods and pathology2020

RAMP1 signaling in immune cells regulates inflammation-associated lymphangiogenesis.

Seri Tsuru, Yoshiya Ito, Hiromi Matsuda, Kanako Hosono, Tomoyoshi Inoue, Shuji Nakamoto, Chie Kurashige, Toshiaki Mishima, Kazutake Tsujikawa, Hirotsugu Okamoto and 1 more

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Laboratory investigation; a journal of technical methods and pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Seri Tsuru *Department of Molecular Pharmacology, Graduate School of Medical Sciences, Kitasato University, Sagamihara, Kanagawa, 252-0374, Japan.
Yoshiya Ito *Department of Molecular Pharmacology, Graduate School of Medical Sciences, Kitasato University, Sagamihara, Kanagawa, 252-0374, Japan.
Hiromi MatsudaDepartment of Anesthesiology, Kitasato University School of Medicine, Sagamihara, Kanagawa, 252-0374, Japan.
Kanako HosonoDepartment of Molecular Pharmacology, Graduate School of Medical Sciences, Kitasato University, Sagamihara, Kanagawa, 252-0374, Japan.
Tomoyoshi InoueDepartment of Molecular Pharmacology, Graduate School of Medical Sciences, Kitasato University, Sagamihara, Kanagawa, 252-0374, Japan.
Shuji NakamotoDepartment of Molecular Pharmacology, Graduate School of Medical Sciences, Kitasato University, Sagamihara, Kanagawa, 252-0374, Japan.
Chie KurashigeDepartment of Anesthesiology, Kitasato University School of Medicine, Sagamihara, Kanagawa, 252-0374, Japan.
Toshiaki MishimaDepartment of Cardiovascular Surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, 252-0374, Japan.
Kazutake TsujikawaLaboratory of Molecular and Cellular Physiology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan.
Hirotsugu OkamotoDepartment of Anesthesiology, Kitasato University School of Medicine, Sagamihara, Kanagawa, 252-0374, Japan.
Masataka MajimaDepartment of Molecular Pharmacology, Graduate School of Medical Sciences, Kitasato University, Sagamihara, Kanagawa, 252-0374, Japan. mmajima@med.kitasto-u.ac.jp.
Kitasato University · JPOsaka University · JP

Funding

Ministry of Education, Culture, Sports, Science and Technology (MEXT) 18H02605Ministry of Education, Culture, Sports, Science and Technology (MEXT) 18K16994Ministry of Education, Culture, Sports, Science and Technology (MEXT) 19K07127Ministry of Education, Culture, Sports, Science and Technology (MEXT) 19K16297
6 · The paper itself

Abstract

Calcitonin gene-related peptide (CGRP) regulates inflammation via signaling through receptor activity-modifying protein (RAMP) 1. Here, we investigated the role of RAMP1 signaling in growth of lymphatic vessels during inflammation. Lymphangiogenesis in the diaphragm of RAMP1-deficient (

Indexed as

InflammationLymphangiogenesisReceptor Activity-Modifying Protein 1AnimalsDiaphragmLymphatic VesselsMacrophagesMaleMiceMice, KnockoutSignal TransductionT-LymphocytesVascular Endothelial Growth FactorsRamp1 protein, mouseReceptor Activity-Modifying Protein 1Vascular Endothelial Growth Factors

Identifiers

PMID31911634
OpenAlexW3000196135

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.