ArticleNature communications2020
Ventromedial prefrontal cortex compression during concept learning.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
80 citing papers in PubMed, 1 synthesis or guideline pooled it, 164 citations in OpenAlex.
- A comprehensive analysis of brain network complexity in task-based fMRI using entropy: systematic review.Brain imaging and behavior · 2026Pooled it
- An abstract relational map emerges in the human medial prefrontal cortex with consolidation.Current biology : CB · 2026Article
- Hippocampo-neocortical interaction as compressive retrieval-augmented generation.Nature communications · 2026Article
- Ventromedial prefrontal cortex supports prototype representations in healthy older adults.Neurobiology of aging · 2026Article
- Categorization is 'baked' into the brain.Nature reviews. Neuroscience · 2026Review
- Increasing representational capacity in the hippocampal-frontoparietal system underlies hierarchical development of temporal memory.Developmental cognitive neuroscience · 2026Review
- Steering through task uncertainty: Evidence for activation modulation over dynamic binding.Psychonomic bulletin & review · 2026Article
- Distinct Hippocampal Mechanisms Support Concept Formation and Updating.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Article
- Neurocomputational modeling of rule abstraction and memorization during probabilistic stimulus-reward learning.iScience · 2026Article
- Data-driven ANN-based visual decoding enables unsupervised functional alignment.Communications biology · 2026Article
- Complementary white matter networks support flexible concept learning.Frontiers in neuroscience · 2026Article
- Hippocampal-prefrontal orchestration supports higher-order learning for creative ideation.Nature communications · 2025Article
- Factorized embedding of goal and uncertainty in the lateral prefrontal cortex guides stably flexible learning.Nature communications · 2025Article
- Adaptive stretching of representations across brain regions and deep learning model layers.Nature communications · 2025Article
- Dynamically shifting from compositional to conjunctive brain representations supports cognitive task learning.Nature communications · 2025Article
- Cognitive Maps in the Prefrontal Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- A compressed code for memory discrimination.bioRxiv : the preprint server for biology · 2025Article
- Fragmentation and multithreading of experience in the default-mode network.Nature communications · 2025Article
- Complex Rule Transfer Recruits Rostral Prefrontal and Ventromedial Prefrontal Neural Networks.Human brain mapping · 2025Article
20 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 3 countries.
Funding
Abstract
Prefrontal cortex (PFC) is thought to support the ability to focus on goal-relevant information by filtering out irrelevant information, a process akin to dimensionality reduction. Here, we test this dimensionality reduction hypothesis by relating a data-driven approach to characterizing the complexity of neural representation with a theoretically-supported computational model of learning. We find evidence of goal-directed dimensionality reduction within human ventromedial PFC during learning. Importantly, by using computational predictions of each participant's attentional strategies during learning, we find that that the degree of neural compression predicts an individual's ability to selectively attend to concept-specific information. These findings suggest a domain-general mechanism of learning through compression in ventromedial PFC.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.