Evidence map›Paper›PMID 31911622›Full record

ArticleSpinal cord2020

Changes in skin-physiology after local heat application using two different methods in individuals with complete paraplegia: a feasibility and safety trial.

Anke Scheel-Sailer, Nushaba Aliyev, Dominique Jud, Simon Annaheim, Yves Harder, Jörg Krebs, Alessia Wildisen, Reto Wettstein

Abstract read
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In one paragraph

Article in Spinal cord, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Anke Scheel-Sailer *Swiss Paraplegic Centre, 6207, Nottwil, Switzerland. anke.scheel-sailer@paraplegie.ch.ORCID http://orcid.org/0000-0003-3820-6664
Nushaba Aliyev *Swiss Paraplegic Centre, 6207, Nottwil, Switzerland.
Dominique Jud *Swiss Paraplegic Centre, 6207, Nottwil, Switzerland.
Simon AnnaheimEmpa, Swiss Federal Laboratories for Biomimetic Membranes and Textiles, Laboratory for Protection and Physiology, 9014, St. Gallen, Switzerland.
Yves HarderDivision of Plastic, Reconstructive and Aesthetic Surgery, Ospedale Regionale di Lugano (ORL), Ente Ospedaliero Cantonale (EOC), 6500, Viganello-Lugano, Switzerland.
Jörg KrebsSwiss Paraplegic Centre, 6207, Nottwil, Switzerland.
Alessia WildisenSwiss Paraplegic Centre, 6207, Nottwil, Switzerland.
Reto WettsteinSwiss Paraplegic Centre, 6207, Nottwil, Switzerland.
Swiss Paraplegic Research · CHUniversity of Basel · CHSwiss Federal Laboratories for Materials Science and Technology · CHSwiss Paraplegic Center · CHUniversity Hospital of Basel · CHUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designInterventional feasibility study.

objectivesTo evaluate safety and effects of local heat preconditioning on skin physiology using water-filtered infrared-A radiation (wIRA) or warm water therapy (wWT) in individuals with spinal cord injury (SCI).

settingAcute and rehabilitation center, specialized in SCI.

methodsA convenience sample of 15 individuals (3 women, 12 men) with complete paraplegia from thoracic levels ranging between T2 and T12 received local heat applications either with wIRA or wWT on the thigh (paralyzed area) and on the upper arm (non-paralyzed area). Local heat was applied during three 30-min cycles, each separated by 30 min rest; thus, the treatment lasted for 180 min. Temperature, blood perfusion, and skin redness were measured at baseline, before and after heat application and 24 h after the last application.

resultsHeat applications with wIRA and wWT were well-tolerated. No burns or any other side effects were detected. Skin temperature (p ≤ 0.008) and blood perfusion (p ≤ 0.013) significantly increased after heat application. Local skin temperature (arm p = 0.004/leg p < 0.001) and blood perfusion (arm p = 0.011/leg p = 0.001) after the first and the second application cycle, respectively, were significantly higher during heat application with wIRA than with wWT. However, skin redness did not change significantly (p = 0.1). No significant differences were observed between the paralyzed and non-paralyzed areas for all parameters immediately, as well as 24 h after the treatment.

conclusionsAlthough both heating methods have been confirmed as safe treatments in this study, further investigations with regard to their efficacy in the context of preconditioning are warranted. SPONSORSHIP: The use of the instruments Hydrosun® 750 Irradiator (Hydrosun Medizintechnik, Germany) and Hilotherm-Calido 6 (Hilotherm GmbH, Germany) was sponsored by the Dr. med. h. c. Erwin Braun Foundation and by Hilotherm GmbH, respectively.

Indexed as

Hot TemperatureAdultArmFeasibility StudiesFemaleHumansInfrared RaysMaleNeurological RehabilitationParaplegiaRegional Blood FlowSkin TemperatureSpinal Cord InjuriesThighThoracic VertebraeWaterWater

Identifiers

PMID31911622
OpenAlexW3000512051

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.