Evidence map›Paper›PMID 31911518›Full record

ArticleBMJ open2020

Optimal dose-fractionation schedule of palliative radiotherapy for patients with bone metastases: a protocol for systematic review and network meta-analysis.

Xiaofang Tang, Qiancheng Hu, Ye Chen, Xin Wang, Xiaofen Li, Ke Cheng, Dan Cao

Abstract read
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaofang TangDepartment of Emergency; Disaster Medical Center, Sichuan University West China Hospital, Chengdu, Sichuan, China.
Qiancheng HuDepartment of Abdominal Oncology, Cancer Center, Sichuan University West China Hospital, Chengdu, Sichuan, China.
Ye ChenDepartment of Abdominal Oncology, Cancer Center, Sichuan University West China Hospital, Chengdu, Sichuan, China.
Xin WangDepartment of Abdominal Oncology, Cancer Center, Sichuan University West China Hospital, Chengdu, Sichuan, China.
Xiaofen LiDepartment of Abdominal Oncology, Cancer Center, Sichuan University West China Hospital, Chengdu, Sichuan, China.
Ke ChengDepartment of Abdominal Oncology, Cancer Center, Sichuan University West China Hospital, Chengdu, Sichuan, China.
Dan CaoDepartment of Abdominal Oncology, Cancer Center, Sichuan University West China Hospital, Chengdu, Sichuan, China caodan316@163.com.ORCID 0000-0002-6709-4932

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe optimal dose-fractionation schedule of palliative radiotherapy has been debated in patients with bone metastases. Our objective is to comprehensively compare multiple fraction schedules with single fraction radiotherapy in terms of efficacy and toxicities by performing a systematic review and network meta-analysis. METHODS AND ANALYSIS: Electronic searches of titles/abstracts of palliative radiotherapy for bone metastases will be performed, using PubMed, Cochrane Library, Embase, ETHICS AND DISSEMINATION: This study will synthesise the evidence regarding dose-fractionation schedule of palliative radiotherapy in patients with bone metastases. We hope the findings from this study will help clinicians and patients select optimum palliative radiotherapy by identifying the optimal dose-fractionation schedule of palliative radiotherapy with the most value in terms of patient-important outcomes. The evidence obtained from network meta-analysis will help to guide head-to-head research in the future. The results will be disseminated through international conference reports and peer-reviewed manuscripts. Ethics review board is not required for this network meta-analysis. PROSPERO REGISTRATION NUMBER: CRD42019135195.

Indexed as

Bone NeoplasmsPalliative CareDose Fractionation, RadiationHumansNeoplasm MetastasisNetwork Meta-Analysis as TopicSystematic Reviews as Topicbone metastasesnetwork meta-analysispalliative radiotherapyprotocol

Identifiers

PMID31911518
PMCPMC6955492

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.