Evidence map›Paper›PMID 31911488›Full record

ArticlemBio2020

Diversification of Campylobacter jejuni Flagellar C-Ring Composition Impacts Its Structure and Function in Motility, Flagellar Assembly, and Cellular Processes.

Louie D Henderson, Teige R S Matthews-Palmer, Connor J Gulbronson, Deborah A Ribardo, Morgan Beeby, David R Hendrixson

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 39 citations in OpenAlex.

  1. TheProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. FliO is an evolutionarily conserved yet diversified core component of the bacterial flagellar type III secretion system.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. A flagellar accessory protein links chemotaxis to surface sensing.bioRxiv : the preprint server for biology · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Novel Antibiofilm Inhibitor Ginkgetin as an Antibacterial Synergist againstInternational journal of molecular sciences · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Louie D Henderson *Department of Life Sciences, Imperial College London, London, United Kingdom.
Teige R S Matthews-Palmer *Department of Life Sciences, Imperial College London, London, United Kingdom.
Connor J GulbronsonDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Deborah A RibardoDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Morgan BeebyDepartment of Life Sciences, Imperial College London, London, United Kingdom m.beeby@imperical.ac.uk david.hendrixson@utsouthwestern.edu.
David R HendrixsonDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA m.beeby@imperical.ac.uk david.hendrixson@utsouthwestern.edu.ORCID 0000-0001-8496-2466
Imperial College London · GBThe University of Texas Southwestern Medical Center · US

Funding

Flagellar Motor Biogenesis in Polarly-Flagellated Bacterial PathogensR01AI065539 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI DAVID R HENDRIXSON · 2006 to 2026
$9.2M
MOLECULAR MICROBIOLOGY TRAINING GRANTT32AI007520 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI Julie K Pfeiffer · 1997 to 2026
$7.0M
Medical Research Council MR/P019374/1NIAID NIH HHS R01 AI065539NIAID NIH HHS T32 AI007520Wellcome Trust FC001179
6 · The paper itself

Abstract

Bacterial flagella are reversible rotary motors that rotate external filaments for bacterial propulsion. Some flagellar motors have diversified by recruiting additional components that influence torque and rotation, but little is known about the possible diversification and evolution of core motor components. The mechanistic core of flagella is the cytoplasmic C ring, which functions as a rotor, directional switch, and assembly platform for the flagellar type III secretion system (fT3SS) ATPase. The C ring is composed of a ring of FliG proteins and a helical ring of surface presentation of antigen (SPOA) domains from the switch proteins FliM and one of two usually mutually exclusive paralogs, FliN or FliY. We investigated the composition, architecture, and function of the C ring of

Indexed as

Bacterial ProteinsBiological EvolutionCampylobacter jejuniFlagellaStructure-Activity RelationshipType III Secretion SystemsBacterial ProteinsType III Secretion SystemsC ringflagellar motorFlhGFliIFliNFliYpolar flagellatype III secretion

Identifiers

PMID31911488
PMCPMC6946799
OpenAlexW2999426149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.