SynthesisJournal of biomechanics2020
Moment-rotation behavior of intervertebral joints in flexion-extension, lateral bending, and axial rotation at all levels of the human spine: A structured review and meta-regression analysis.
Synthesis in Journal of biomechanics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- In Silico Meta-Analysis of Boundary Conditions for Experimental Tests on the Lumbar Spine.Annals of biomedical engineering · 2022Pooled it
- A Muscle-Driven Lumbar Spine Model for Predicting Vibration-Induced Spinal Loads with Adaptive Control.Annals of biomedical engineering · 2026Article
- A Biomechanical Analysis of Two-Person Emergency Patient Lifting Techniques Using Motion Capture and Ergonomic Assessment.Sensors (Basel, Switzerland) · 2026Article
- Structural design and biomechanical analysis of anti- subsidence gradient porous artificial vertebrae combined with a topology framework.BMC musculoskeletal disorders · 2026Article
- Adequate Segmentation in Marker-Based Motion Capture Studies for Hyperflexion and Hyperextension Lumbar Exercises.Bioengineering (Basel, Switzerland) · 2025Article
- Article
- Combined Rigid-Flexible Multibody Analysis Reveals Reduced Pedicle Screw Loads in Short-Segment Fixation for Decompressed Lumbar Spine Stabilization.Annals of biomedical engineering · 2025Article
- Bending properties of human cartilaginous ribs and costal cartilage material vary with age, sex, and calcification.JBMR plus · 2025Article
- Variability of intervertebral joint stiffness between specimens and spine levels.Frontiers in bioengineering and biotechnology · 2024Article
- Identification of a lumped-parameter model of the intervertebral joint from experimental data.Frontiers in bioengineering and biotechnology · 2024Article
- Diabetes-related Screw Loosening: The Distinction of Surgical Sites and the Relationship among Diabetes, Implant Stabilization and Clinical Outcomes.Orthopaedic surgery · 2023Article
- A novel artificial vertebral implant with Gyroid porous structures for reducing the subsidence and mechanical failure rate after vertebral body replacement.Journal of orthopaedic surgery and research · 2023Article
- Off-Axis Loading Fixture for Spine Biomechanics: Combined Compression and Bending.Journal of biomechanical engineering · 2023Article
- Development and Validation of a Novel In Vitro Joint Testing System for Reproduction of In Vivo Dynamic Muscle Force.Bioengineering (Basel, Switzerland) · 2023Article
- Effects of occipital-atlas stabilization on the upper cervical spine rotation combinations: an in vitro study.Scientific reports · 2023Article
- Biomechanical effects of lumbar fusion surgery on adjacent segments using musculoskeletal models of the intact, degenerated and fused spine.Scientific reports · 2021Article
- In vivo measurements of spinal stiffness according to a stepwise increase of axial load.European journal of applied physiology · 2021Article
- Patterns of Load-to-Strength Ratios Along the Spine in a Population-Based Cohort to Evaluate the Contribution of Spinal Loading to Vertebral Fractures.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2021Article
- Influence of Axial Load and a 45-Degree Flexion Head Position on Cervical Spinal Stiffness in Healthy Young Adults.Frontiers in physiology · 2021Article
- Spinal Compressive Forces in Adolescent Idiopathic Scoliosis With and Without Carrying Loads: A Musculoskeletal Modeling Study.Frontiers in bioengineering and biotechnology · 2020Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Spinal intervertebral joints are complex structures allowing motion in multiple directions, and many experimental studies have reported moment-rotation response. However, experimental methods, reporting of results, and levels of the spine tested vary widely, and a comprehensive assessment of moment-rotation response across all levels of the spine is lacking. This review aims to characterize moment-rotation response in a consistent manner for all levels of the human spine. A literature search was conducted in PubMed for moment versus rotation data from mechanical testing of intact human cadaveric intervertebral joint specimens in flexion-extension, lateral bending, and axial rotation. A total of 45 studies were included, providing data from testing of an estimated 1,648 intervertebral joints from 518 human cadavers. We used mixed-effects regression analysis to create 75 regression models of moment-rotation response (25 intervertebral joints × 3 directions). We found that a cubic polynomial model provides a good representation of the moment-rotation behavior of most intervertebral joints, and that compressive loading increases rotational stiffness throughout the spine in all directions. The results allow for the direct evaluation of intervertebral ranges of motion across the whole of the spine for given loading conditions. The random-effects outcomes, representing standard deviations of the model coefficients across the dataset, can aid understanding of normal variations in moment-rotation responses. Overall these results fill a large gap, providing the first realistic and comprehensive representations of moment-rotation behavior at all levels of the spine, with broad implications for surgical planning, medical device design, computational modeling, and understanding of spine biomechanics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.