ArticleHealth and quality of life outcomes2020
Factors associated with quality of life of adult patients with acute leukemia and their family caregivers in China: a cross-sectional study.
Article in Health and quality of life outcomes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Effects of a WeChat-based multimodal psychoeducational intervention on psychological well-being and quality of life in acute leukaemia patients in China: a randomised controlled trial.Journal of cancer survivorship : research and practice · 2022Trial
- Designing a need-based program for relieving psychological distress of family caregivers of leukemia patients: a randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Trial
- Molecular response and quality of life in chronic myeloid leukemia patients treated with intermittent TKIs: First interim analysis of OPTkIMA study.Cancer medicine · 2021Trial
- Physical activity trajectories and associated factors in patients with lung cancer undergoing chemotherapy: A longitudinal study.Asia-Pacific journal of oncology nursing · 2026Article
- Resilience as an indirect pathway linking depressive symptoms and quality of life among family caregivers of hospitalized lung cancer patients in Northern Vietnam.Tropical medicine and health · 2026Article
- Cognitive appraisal, negative coping, and family resilience among acute leukemia patients and their primary family caregivers: an actor-partner interdependence mediation model of quality of life.Frontiers in psychology · 2026Article
- Article
- Health fitness, physical activity, and quality of life in patients undergoing first chemotherapy for lung cancer: a cross-sectional study.Scientific reports · 2025Article
- Budget impact analysis of revumenib for the treatment of relapsed or refractory acute leukemias with aJournal of managed care & specialty pharmacy · 2025Article
- The holistic model of leukaemia survivorship care: derived from a qualitative exploration of leukaemia survivorship.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Comparison of the sense of spousal support, anxiety, depression and their relationship to fear of cancer recurrence between lymphoma patients and their spouses: A cross-sectional study in China.Journal of cancer survivorship : research and practice · 2025Article
- Quality of life among Indonesian family caregivers caring for dependent older persons with type 2 diabetes mellitus in the community: A cross-sectional, correlational study.Belitung nursing journal · 2025Article
- Family participation in dignity interventions for patients with cancer receiving palliative care: a scoping review protocol.BMJ open · 2024Article
- The effect of self-care education with smart phone applications on the severity of nausea and vomiting after stem cell transplantation in leukemia patients.Hematology, transfusion and cell therapy · 2024Article
- Symptom experiences and self-management strategies of patients with haematological malignancy undergoing chemotherapy: A qualitative study.Asia-Pacific journal of oncology nursing · 2024Article
- Needs and Experiences With Health Care Providers of Adult Rare Disease Patients and Caregivers of People With Rare Diseases: Protocol for a Qualitative Study.JMIR research protocols · 2024Article
- Understanding Quality of Life in Patients With Acute Leukemia, a Global Survey.Journal of patient-centered research and reviews · 2023Article
- Effects of different psychological interventions on quality of life and remission rate in patients with acute leukemia receiving chemotherapy: A randomized controlled trial.Frontiers in psychology · 2023Article
- Quality of Life of Family Caregivers of Cancer Patients in a Developing Nation.Asian Pacific journal of cancer prevention : APJCP · 2022Article
- Quality of life and related factors in caregivers of children with cancer in Iran.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundAcute leukemia (AL) not only impairs the quality of life (QOL) of patients, but also affects that of their family caregivers (FCs). Studies on QOL of AL patients and their FCs are limited. This study aimed to evaluate the QOL of AL patients and their FCs, and to explore the factors associated with QOL of patients and of FCs.
methodsA multicenter cross-sectional study was conducted. The QOL of 196 patient-FC dyads was assessed. The Functional Assessment of Cancer Therapy-Leukemia (FACT-Leu) was used for patients, and the 36-item Short-Form Health Survey (SF-36) was used for FCs. Independent-samples t-tests or one-way analysis of variance were used to compare QOL subscale scores between groups with different sociodemographic/clinical characteristics. Multiple regression analysis was conducted to identify the factors associated with QOL of AL patients and their FCs.
resultsThe total FACT-Leu score for AL patients was 76.80 ± 16.44, and the physical component summary (PCS) and mental component summary (MCS) scores for FCs were 64.67 ± 15.44 and 52.50 ± 13.49, respectively. All QOL subscales for patients (t = 12.96-34.73, p < 0.001) and FCs (t = 2.55-14.36, p < 0.05), except role emotional (t = - 0.01, p = 0.993), were lower than those reported in previous studies. Sex, employment, and chemotherapy were significantly associated with total FACT-Leu score in AL patients (p < 0.05). Age, sex, marital status, education, employment, and relationship to patients were significantly associated with SF-36 PCS or MCS (p < 0.05).
conclusionsAL patients and their FCs both have lower QOL than the population in previous studies. These findings suggest that not only AL patients' physical and mental health but also overall family QOL should be assessed. Interventions supporting patient-FC dyads should be developed to improve their QOL.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.