ArticleBMC infectious diseases2020
First report of Cryptosporidium viatorum and Cryptosporidium occultus in humans in China, and of the unique novel C. viatorum subtype XVaA3h.
Article in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Prevalence, Genetic Diversity, and Zoonotic Transmission Potential of Cryptosporidium spp. in Snakes: A Systematic Review and Meta-Analysis.Veterinary medicine and science · 2026Pooled it
- The history of cryptosporidiosis.Parasites & vectors · 2026Review
- Molecular characterization of Cryptosporidium spp. in goats (Capra hircus) from Zhejiang Province, China: evidence of zoonotic species and subtypes.BMC microbiology · 2026Article
- 18S/28S rDNA metabarcoding identifies Cryptosporidium parvum and Blastocystis ST1 as the predominant intestinal protozoa in hospital patients from Changchun, Northeast China.Parasites & vectors · 2025Article
- Prevalence and molecular characterization ofFood and waterborne parasitology · 2025Article
- Prevalence and novel genetic characteristics of Cryptosporidium spp. in wild rodents in the northern foothills of the Dabie Mountains, southeast Henan Province, China.PLoS neglected tropical diseases · 2025Article
- Occurrence and Molecular Characterization ofMicroorganisms · 2025Article
- Review
- Food and Waterborne Cryptosporidiosis from a One Health Perspective: A Comprehensive Review.Animals : an open access journal from MDPI · 2024Review
- Molecular characterizations of Cryptosporidium spp. in brown rat (Rattus norvegicus) from an animal feedlot in Xinjiang, China.Parasitology research · 2024Article
- Rodent-adaptedOne health (Amsterdam, Netherlands) · 2024Article
- Molecular characterization ofOne health (Amsterdam, Netherlands) · 2024Article
- Detection and Molecular Diversity ofAnimals : an open access journal from MDPI · 2024Article
- Molecular characterization ofFrontiers in veterinary science · 2024Article
- Molecular characterization ofFrontiers in veterinary science · 2024Article
- Molecular identification and genetic characteristics of Cryptosporidium spp., Giardia duodenalis, and Enterocytozoon bieneusi in human immunodeficiency virus/acquired immunodeficiency syndrome patients in Shanghai, China.Parasites & vectors · 2023Article
- Genetic diversity ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022Article
- An Update on ZoonoticAnimals : an open access journal from MDPI · 2021Review
- Molecular Epidemiology of Human Cryptosporidiosis in Low- and Middle-Income Countries.Clinical microbiology reviews · 2021Review
- The Age-RelatedAnimals : an open access journal from MDPI · 2021Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCryptosporidium is a genus of common intestinal protozoa, members of which cause diarrhea in a wide variety of hosts. Previous studies on Cryptosporidium in China have mainly focused on diarrhea sufferers, children, and immunodeficient individuals such as HIV/AIDS patients. However, the epidemiological characteristics of Cryptosporidium in the population in rural areas remain unclear. Herein, we investigated the prevalence of, and risk factors for, Cryptosporidium in rural areas of Binyang County, Guangxi Zhuang Autonomous Region, China, and genetically characterized the Cryptosporidium isolates we obtained.
methodsFrom August to December 2016, two villages in Binyang County, Guangxi, were sampled using a random cluster sampling method. Fresh fecal samples were collected from all eligible residents (residence time > 6 months). Molecular characterization of Cryptosporidium was carried out based on its SSU rRNA, gp60, actin and hsp70 gene sequences. Fisher's exact test were conducted to assess the risk factors for Cryptosporidium infection.
resultsA total of 400 fecal samples were collected from 195 males (48.8%) and 205 females (51.2%). Two samples (0.5%) were positive for Cryptosporidium and were identified as C. viatorum and C. occultus respectively. Moreover, a new C. viatorum subtype XVaA3h was identified based on the sequence of the gp 60 gene.
conclusionsTo our knowledge, this is the first report of C. viatorum and C. occultus infections in humans in China and of C. viatorum subtype XVaA3h. The findings provide important information on the prevalence of Cryptosporidium in the Chinese population, and expand the range of Cryptosporidium species known to infect people in China.
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