Evidence map›Paper›PMID 31910809›Full record

ReviewBMC cardiovascular disorders2020

Advances in transcatheter mitral and tricuspid therapies.

Pavel Overtchouk, Nicolo Piazza, Juan Granada, Osama Soliman, Bernard Prendergast, Thomas Modine

Open access · goldAbstract readReview
In one paragraph

Review in BMC cardiovascular disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 76 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Macrophages modulate stiffness-related foreign body responses through plasma membrane deformation.Proceedings of the National Academy of Sciences of the United States of America · 2023
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  7. Review
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  10. Review
  11. Review
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  14. Patient with heart failure: importance to treat valvular diseases.European heart journal supplements : journal of the European Society of Cardiology · 2020
    Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 7 countries.

Pavel OvertchoukDepartment of Cardiology, University Hospital of Bern, Bern, Switzerland.
Nicolo PiazzaInterventional cardiology, McGill University Health Centre, 1001 Boulevard Décarie, Montréal, QC, H4A 3J1, Canada.
Juan GranadaCardiovascular Research Foundation, Columbia University Medical Center, CRF Skirball Center for Innovation, New York, USA.
Osama SolimanThoraxcenter, Erasmus University Medical Center Rotterdam, Medical Director Structural Heart & Heart Failure Research, Cardialysis, Rotterdam, Netherlands.
Bernard PrendergastDepartment of Cardiology, St Thomas' Hospital, London, UK.
Thomas ModineCardiology and Cardiovascular Surgery Department, Heart Valve Center, Institut Cœur Poumon CHU de Lille, 2 Av Oscar Lambret, 59037, Lille, France. thomasmodine@gmail.com.ORCID 0000-0003-4169-3766
Centre Hospitalier Universitaire de Lille · FRColumbia University Irving Medical Center · USErasmus MC · NLMcGill University Health Centre · CASt Thomas' Hospital · GBUniversity Hospital of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile rheumatic mitral stenosis has been effectively treated percutaneously for more than 20 years, mitral and tricuspid regurgitation treatment appear as a contemporary unmet need. The advent of transcatheter therapies offer new treatment options to often elderly and frail patients at high risk for open surgery. We aimed at providing an updated review of fast-growing domain of transcatheter mitral and tricuspid technology. MAIN BODY: We reviewed the existing literature on mitral and tricuspid transcatheter therapies. Mitraclip is becoming an established therapy for secondary mitral regurgitation in selected patients with disproportionately severe regurgitation associated with moderate left ventricle dysfunction. Evidence is less convincing for primary mitral regurgitation. Transcatheter mitral valve replacement is a promising emerging alternative to transcatheter repair, for secondary as well as primary mitral regurgitation. But further development is needed to improve delivery. Transcatheter tricuspid intervention arrives late after similar technologies have been developed for aortic and mitral valves and is currently at its infancy. This is likely due in part to previously under-recognized impact of tricuspid regurgitation on patient outcomes. Edge-to-edge repair is the most advanced transcatheter solution in development. Data on tricuspid annuloplasty and replacement is limited, and more research is warranted.

conclusionThe future appears bright for transcatheter mitral therapies, albeit their place in clinical practice is yet to be clearly defined. Tricuspid transcatheter therapies might address the unmet need of tricuspid regurgitation treatment.

Indexed as

Heart Valve Prosthesis ImplantationMitral Valve AnnuloplastyHeart Valve DiseasesHeart Valve ProsthesisHumansMitral ValvePostoperative ComplicationsProsthesis DesignRecovery of FunctionRisk FactorsTreatment OutcomeTricuspid ValveMitral repairMitral replacementTMVITMVRTranscatheter mitral therapyTranscatheter tricuspid therapyTricuspid repairTricuspid replacementTTVI

Identifiers

PMID31910809
PMCPMC6945613
OpenAlexW3008927185

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.