Evidence map›Paper›PMID 31910806›Full record

ArticleBMC anesthesiology2020

Identifying appropriate outcomes to help evaluate the impact of the Canadian Guideline for Safe and Effective Use of Opioids for Non-Cancer Pain.

Michael Allen, Beth Sproule, Peter MacDougall, Andrea Furlan, Laura Murphy, Victoria Borg Debono, Norman Buckley

Open access · goldAbstract read
In one paragraph

Article in BMC anesthesiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Michael AllenContinuing Professional Development, Dalhousie University, Halifax, Canada.
Beth SprouleCentre for Addiction & Mental Health (CAMH), Toronto, Canada.
Peter MacDougallDepartment of Anesthesia, Pain Management and Perioperative Medicine, Dalhousie University, Halifax, Canada.
Andrea FurlanInstitute for Work & Health, Toronto, Canada.
Laura MurphyLeslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada.
Victoria Borg DebonoMichael G. DeGroote National Pain Centre, McMaster University, Hamilton, Canada.
Norman BuckleyMichael G. DeGroote National Pain Centre, McMaster University, Hamilton, Canada. buckleyn@mcmaster.ca.ORCID 0000-0002-1031-6813
Dalhousie University · CAMcMaster University · CACentre for Addiction and Mental Health · CAUniversity Health Network · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Canadian Guideline for Safe and Effective Use of Opioids for Chronic Non-Cancer Pain (COG) was developed in response to increasing rates of opioid-related hospital visits and deaths in Canada, and uncertain benefits of opioids for chronic non-cancer pain (CNCP). Following publication, we developed a list of evaluable outcomes to assess the impact of this guideline on practice and patient outcomes.

methodsA working group at the National Pain Centre at McMaster University used a modified Delphi process to construct a list of clinical and patient outcomes important in assessing the uptake and application of the COG. An advisory group then reviewed this list to determine the relevance and feasibility of each outcome, and identified potential data sources. This feedback was reviewed by the National Faculty for the Guideline, and a National Advisory Group that included the creators of the COG, resulting in the final list of 5 priority outcomes.

resultsFive outcomes were judged clinically important and feasible to measure: 1) Effects of opioids for CNCP on quality of life, 2) Assessment of patient's risk of addiction before starting opioid therapy, 3) Monitoring patients on opioid therapy for aberrant drug-related behaviour, 4) Mortality rates associated with prescription opioid overdose and 5) Use of treatment agreements with patients before initiating opioid therapy for CNCP. Data sources for these outcomes included patient's medical charts, e-Opioid Manager, prescription monitoring programs and administrative databases.

conclusionMeasuring the impact of best practice guidelines is infrequently done. Future research should consider capturing the five outcomes identified in this study to evaluate the impact of the COG in promoting evidence-based use of opioids for CNCP.

Indexed as

Guidelines as TopicAnalgesics, OpioidCanadaCancer PainChronic PainDelphi TechniqueDrug OverdoseGuideline AdherenceHumansOpioid-Related DisordersPain ManagementPatient Education as TopicRiskTreatment OutcomeAnalgesics, OpioidChronic non-Cancer painModified Delphi processNational Pain CentreOpioidsOutcomes to evaluate guideline impact

Identifiers

PMID31910806
PMCPMC6945645
OpenAlexW2999515629

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.