Evidence map›Paper›PMID 31910803›Full record

ArticleBMC pediatrics2020

Study protocol of a randomized controlled trial of home-based computerized executive function training for children with cerebral palsy.

María García-Galant, Montse Blasco, Lee Reid, Kerstin Pannek, David Leiva, Olga Laporta-Hoyos, Júlia Ballester-Plané, Júlia Miralbell, Xavi Caldú, Xènia Alonso and 7 more

2 registry-linked trialsOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMC pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04025749 nacompletednot on this map

Executive Training in Cerebral Palsy: Participation, Quality of Life and Brain Connectivity

TypeinterventionalSponsorUniversity of BarcelonaRan2017 to 2022Enrolled60ConditionsCerebral PalsyArmsComputerized Executive Functions training, Care as usual
NCT06288971 nanot yet recruitingnot on this mapstarted 2024, after this paper: background citation

Personalized Innovative Intervention Pathways to Promote Executive Function in Children With Cerebral Palsy

TypeinterventionalSponsorIRCCS Fondazione Stella MarisRan2024 to 2027Enrolled40ConditionsExecutive Functions in Cerebral PalsyArmsSelf-adaption web-based software for the rehabilitation of EF and visuo-spatial abilities, Tele-rehabilitation of EF and specific cognitive processes underlying academic skills, Game-based tools for the rehabilitation of EF and motor planning
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 2 countries.

María García-GalantDepartament de Psicologia Clínica i Psicobiologia, Universitat de Barcelona, Passeig Vall d'Hebron 171, Barcelona, 08035, Spain.
Montse BlascoDepartament de Psicologia Clínica i Psicobiologia, Universitat de Barcelona, Passeig Vall d'Hebron 171, Barcelona, 08035, Spain.
Lee ReidAustralian e-Health Research Centre, Commonwealth Scientific and Industrial Research Organisation, Brockway 65, Brisbane, 6014, Queensland, Australia.
Kerstin PannekAustralian e-Health Research Centre, Commonwealth Scientific and Industrial Research Organisation, Brockway 65, Brisbane, 6014, Queensland, Australia.
David LeivaDepartament de Psicologia Social i Psicologia Quantitativa, Universitat de Barcelona, Barcelona, 08035, Spain.
Olga Laporta-HoyosDepartament de Psicologia Clínica i Psicobiologia, Universitat de Barcelona, Passeig Vall d'Hebron 171, Barcelona, 08035, Spain.
Júlia Ballester-PlanéDepartament de Psicologia Clínica i Psicobiologia, Universitat de Barcelona, Passeig Vall d'Hebron 171, Barcelona, 08035, Spain.
Júlia MiralbellDepartament de Psicologia Clínica i Psicobiologia, Universitat de Barcelona, Passeig Vall d'Hebron 171, Barcelona, 08035, Spain.
Xavi CaldúDepartament de Psicologia Clínica i Psicobiologia, Universitat de Barcelona, Passeig Vall d'Hebron 171, Barcelona, 08035, Spain.
Xènia AlonsoServei de Neurologia, Hospital Universitari Sant Joan de Déu, Passeig Sant Joan de Déu 2, Barcelona, 08950, Spain.
Esther Toro-TamargoServei de Rehabilitació i Medicina Física, Hospital Universitari Vall d'Hebron, Passeig Vall d'Hebron 119-129, Barcelona, 08035, Spain.
Mar Meléndez-PlumedServei de Rehabilitació i Medicina Física, Hospital Universitari Vall d'Hebron, Passeig Vall d'Hebron 119-129, Barcelona, 08035, Spain.
Francisca GimenoServeis de Rehabilitació, Associació de la Paràlisi Cerebral (ASPACE), Camí Tres Pins 31-35, Barcelona, 08038, Spain.
Marc CoronasDepartament de Cognició, Desenvolupament i Psicologia de l'Educació, Universitat de Barcelona, Passeig Vall d'Hebron 171, Barcelona, 08035, Spain.
Emili Soro-CamatsDepartament de Cognició, Desenvolupament i Psicologia de l'Educació, Universitat de Barcelona, Passeig Vall d'Hebron 171, Barcelona, 08035, Spain.
Roslyn BoydQueensland Cerebral Palsy and Rehabilitation Research Centre, The University of Queensland, Graham 62, Brisbane, 4101, Queensland, Australia.
Roser PueyoDepartament de Psicologia Clínica i Psicobiologia, Universitat de Barcelona, Passeig Vall d'Hebron 171, Barcelona, 08035, Spain. rpueyo@ub.edu.
Universitat de Barcelona · ESInstitut de Recerca Sant Joan de DéuVall d'Hebron Hospital Universitari · ESAssociació de la Paràlisi Cerebral · ESAustralian e-Health Research Centre · AUCerebral Palsy Alliance · AUHospital Sant Joan de Déu Barcelona · ESUniversity of Queensland · AU

Funding

Agència de Gestió d'Ajuts Universitaris i de Recerca 2017SGR0748Ministerio de Economía y Competitividad PSI2016-75979- RQueensland Government R-09964001Universitat de Barcelona APIF_2018-2019
6 · The paper itself

Abstract

backgroundCerebral palsy (CP) is frequently associated with specific cognitive impairments, such as executive dysfunction which are related to participation and quality of life (QOL). The proposed study will examine whether a computerized executive function (EF) training programme could provide superior benefits for executive functioning, participation, QOL and brain plasticity, as compared to usual care.

methodsA single-blind randomized controlled trial (RCT) design will be performed. Thirty children with CP aged 8 to 12 years will participate in a home-based computerized multi-modal executive training programme (12 weeks, 5 days a week, 30 min a day training, total dose = 30 h). Thirty children with CP matched by age, sex, motor and intelligence quotient (IQ) will compose the waitlist group. Cognitive, behavioural, emotional, participation and QOL measures will be obtained at three time points: before, immediately after and 9 months after completing the training. Additionally, structural and functional (resting state) magnetic resonance images (MRI) will be obtained in a subsample of 15 children from each group. Outcomes between groups will be compared following standard principles for RCTs. DISCUSSION: The study will test whether the cognitive training programme exerts a positive effect not only on neuropsychological and daily functioning of children with CP but also on other measures such as participation and QOL. We will also use brain MRI to test brain functional and structural changes after the intervention. If this on-line and home-based training programme proves effective, it could be a cost-effective intervention with short- and long-term effects on EF, participation or QOL in CP.

trial registrationClinicalTrials.gov: NCT04025749. Registered 19 July 2019. Retrospectively registered.

Indexed as

Cerebral PalsyCognitive DysfunctionBrainChildExecutive FunctionHumansMagnetic Resonance ImagingRandomized Controlled Trials as TopicTreatment OutcomeCerebral palsyCognitive trainingComputerized therapyExecutive functionsNeuroimagingParticipationQuality of life

Identifiers

PMID31910803
PMCPMC6945450
OpenAlexW2998872376

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.