Evidence map›Paper›PMID 31910653›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2020

Nonlabeling and quantitative assessment of chondrocyte viability in articular cartilage with intrinsic nonlinear optical signatures.

Yang Li, Xun Chen, Beckham Watkins, Neal Saini, Steven Gannon, Elizabeth Nadeau, Russell Reeves, Bruce Gao, Vincent Pelligrini, Hai Yao and 2 more

Abstract read
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Assessing the Impact of Partial Decellularization on Tracheal Chondrocytes and Extracellular Matrix in Airway Reconstruction.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yang LiDepartment of Bioengineering, Clemson University, Clemson, SC 29634, USA.
Xun ChenDepartment of Bioengineering, Clemson University, Clemson, SC 29634, USA.
Beckham WatkinsCollege of Charleston, Charleston, SC 29424, USA.
Neal SainiCollege of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.
Steven GannonDepartment of Bioengineering, Clemson University, Clemson, SC 29634, USA.
Elizabeth NadeauCollege of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.
Russell ReevesCollege of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.
Bruce GaoDepartment of Bioengineering, Clemson University, Clemson, SC 29634, USA.
Vincent PelligriniDepartment of Bioengineering, Clemson University, Clemson, SC 29634, USA.
Hai YaoDepartment of Bioengineering, Clemson University, Clemson, SC 29634, USA.
Jeremy MercuriDepartment of Bioengineering, Clemson University, Clemson, SC 29634, USA.
Tong YeDepartment of Bioengineering, Clemson University, Clemson, SC 29634, USA.ORCID 0000-0003-1017-6969

Funding

South Carolina IDeA Networks of Biomedical Research (SC INBRE V)P20GM103499 · NIGMS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI EDIE C GOLDSMITH · 2012 to 2026
$61.0M
Translational Science Laboratory Shared ResourceP30CA138313 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Jian Ouyang · 2009 to 2026
$42.7M
Tissue Structural and Neural Remodeling in Human Sacroiliac JointP20GM121342 · NIGMS · CLEMSON UNIVERSITY · PI Shangping Wang · 2018 to 2026
$24.7M
NCI NIH HHS P30 CA138313NIGMS NIH HHS P20 GM103499NIGMS NIH HHS P20 GM121342
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Nonlinear DynamicsOptical ImagingAnimalsCartilage, ArticularCell DeathCell SurvivalChondrocytesCollagenFeasibility StudiesMaleNormal DistributionRats, Sprague-DawleyReproducibility of ResultsRhodaminesROC CurveSpectrometry, FluorescenceCollagenrhodamine BRhodaminesautofluorescenceCARTILAGEChondrocyte viabilitylabel-free tissue imagingnonlinear optical microscopysecond harmonic generation microscopy

Identifiers

PMID31910653
PMCPMC7370603

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.